製品の概要

  • 製品名Anti-Fascin antibody [EPR2681]
    Fascin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR2681] to Fascin
  • アプリケーション適用あり: WB, Flow Cytmore details
    適用なし: ICC,IHC-P or IP
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide, corresponding to internal sequence amino acids 435-460 of Human Fascin

  • ポジティブ・コントロール
    • HeLa, SH-SY5Y and K-562 cell lysates
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab108607 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Predicted molecular weight: 55 kDa.
Flow Cyt 1/500 - 1/1000. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 追加情報Is unsuitable for ICC,IHC-P or IP.
  • ターゲット情報

    • 機能Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
    • 組織特異性Ubiquitous.
    • 配列類似性Belongs to the fascin family.
    • ドメインComposed of four beta-trefoil domains.
    • 翻訳後修飾Phosphorylation on Ser-39 inhibits the actin-binding ability of fascin.
    • 細胞内局在Cytoplasm > cytoskeleton. Cell projection > filopodium. Cell projection > invadopodium.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 55 kDa actin bundling protein antibody
      • 55 kDa actin-bundling protein antibody
      • Actin bundling protein antibody
      • actin bundling protein, 55-KD antibody
      • FAN 1 antibody
      • FAN1 antibody
      • Fascin 1 antibody
      • Fascin actin bundling protein 1 antibody
      • Fascin antibody
      • Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuratus) antibody
      • Fascin homolog 1 antibody
      • Fascin, sea urchin, homolog of, 1 antibody
      • Fascin1 antibody
      • FLJ38511 antibody
      • FSCN 1 antibody
      • FSCN1 antibody
      • FSCN1_HUMAN antibody
      • HSN antibody
      • p55 antibody
      • Singed (Drosophila) like (sea urchin fascin homolog like) antibody
      • Singed drosophila homolog like antibody
      • Singed like (fascin homolog sea urchin) (Drosophila) antibody
      • Singed like (fascin homolog sea urchin) antibody
      • Singed like protein antibody
      • Singed, drosophila, homolog of antibody
      • Singed-like protein antibody
      • SNL antibody
      • Strongylocentrotus purpuratus antibody
      see all

    Anti-Fascin antibody [EPR2681] 画像

    • All lanes : Anti-Fascin antibody [EPR2681] (ab108607) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : SH-SY5Y cell lysate
      Lane 3 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 55 kDa
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    Anti-Fascin antibody [EPR2681] (ab108607) 使用論文

    ab108607 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab108607.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"