製品の概要
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製品名Anti-Fas Ligand antibody [MFL3] (Phycoerythrin)
Fas Ligand 一次抗体 製品一覧 -
製品の詳細Armenian Hamster monoclonal [MFL3] to Fas Ligand (Phycoerythrin)
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標識Phycoerythrin. Ex: 488nm, Em: 575nm
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アプリケーション適用あり: Flow Cytmore details
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種交差性交差種: Mouse
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免疫原
B6 mouse FasL cDNA-transfected baby hamster kidney (B6 FasL/BHK) cells.
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ポジティブ･コントロール
- Mouse Fas Ligand transfected cells and activated T cells
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C.
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バッファーPreservative: 0.09% Sodium Azide
Constituents: PBS, 150mM Sodium chloride, pH 7.2 -
Concentration information loading... -
精製度Protein G purified
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ポリ/モノモノクローナル
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クローン名MFL3
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アイソタイプIgG
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研究分野
アプリケーション
Our Abpromise guarantee covers the use of ab93566 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
追加情報
Flow Cyt: Use 0.5 - 1µg for 105 - 108 cells in a final volume of 100µL.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.
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関連疾患Defects in FASLG are the cause of autoimmune lymphoproliferative syndrome type 1B (ALPS1B) [MIM:601859]; also known as Canale-Smith syndrome (CSS). ALPS is a childhood syndrome involving hemolytic anemia and thrombocytopenia with massive lymphadenopathy and splenomegaly.
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配列類似性Belongs to the tumor necrosis factor family.
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翻訳後修飾N-glycosylated.
The soluble form derives from the membrane form by proteolytic processing. -
細胞内局在Cell membrane. Secreted. May be released into the extracellular fluid, probably by cleavage form the cell surface.
- Information by UniProt
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参照データベース
- Entrez Gene: 14103 Mouse
- SwissProt: P41047 Mouse
- Unigene: 3355 Mouse
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別名
- ALPS1B antibody
- Apoptosis (APO 1) antigen ligand 1 antibody
- Apoptosis antigen ligand 1 antibody
see all
Anti-Fas Ligand antibody [MFL3] (Phycoerythrin) 画像
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Flow Cytometry - Fas Ligand antibody (Phycoerythrin) (ab93566)Surface staining of mouse Fas Ligand transfected cells with 0.5µg ab93566. Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.
プロトコール
Anti-Fas Ligand antibody [MFL3] (Phycoerythrin) (ab93566) 使用論文
ab93566 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"