Anti-Fas Ligand 抗体 [MFL3] (Phycoerythrin) (ab93566)

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製品の概要

  • 製品名
    Anti-Fas Ligand antibody [MFL3] (Phycoerythrin)
    Fas Ligand 一次抗体 製品一覧
  • 製品の詳細
    Armenian Hamster monoclonal [MFL3] to Fas Ligand (Phycoerythrin)
  • 由来種
    Armenian hamster
  • 標識
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • アプリケーション
    適用あり: Flow Cytmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    B6 mouse FasL cDNA-transfected baby hamster kidney (B6 FasL/BHK) cells.

  • ポジティブ･コントロール
    • Mouse Fas Ligand transfected cells and activated T cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab93566 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報
    Flow Cyt: Use 0.5 - 1µg for 105 - 108 cells in a final volume of 100µL.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • ターゲット情報

    • 機能
      Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.
    • 関連疾患
      Defects in FASLG are the cause of autoimmune lymphoproliferative syndrome type 1B (ALPS1B) [MIM:601859]; also known as Canale-Smith syndrome (CSS). ALPS is a childhood syndrome involving hemolytic anemia and thrombocytopenia with massive lymphadenopathy and splenomegaly.
    • 配列類似性
      Belongs to the tumor necrosis factor family.
    • 翻訳後修飾
      N-glycosylated.
      The soluble form derives from the membrane form by proteolytic processing.
    • 細胞内局在
      Cell membrane. Secreted. May be released into the extracellular fluid, probably by cleavage form the cell surface.
    • Information by UniProt
    • 参照データベース
      • 別名
        • ALPS1B antibody
        • Apoptosis (APO 1) antigen ligand 1 antibody
        • Apoptosis antigen ligand 1 antibody
        • Apoptosis antigen ligand antibody
        • APT1LG1 antibody
        • APTL antibody
        • CD178 antibody
        • CD178 antigen antibody
        • CD95 ligand antibody
        • CD95-L antibody
        • CD95L antibody
        • CD95L protein antibody
        • Fas antigen ligand antibody
        • Fas L antibody
        • Fas ligand (TNF superfamily member 6) antibody
        • Fas ligand antibody
        • FASL antibody
        • Fasl Fas ligand (TNF superfamily member 6) antibody
        • FASLG antibody
        • Generalized lymphoproliferative disease antibody
        • Gld antibody
        • soluble form antibody
        • TNFL6_HUMAN antibody
        • TNFSF6 antibody
        • Tumor necrosis factor (ligand) superfamily member 6 antibody
        • Tumor necrosis factor ligand superfamily member 6 antibody
        see all

      画像

      • Flow Cytometry - Anti-Fas Ligand antibody [MFL3] (Phycoerythrin) (ab93566)
        Flow Cytometry - Anti-Fas Ligand antibody [MFL3] (Phycoerythrin) (ab93566)
        Surface staining of mouse Fas Ligand transfected cells with 0.5µg ab93566. Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.

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      参考文献

      ab93566 has not yet been referenced specifically in any publications.

      ab93566 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

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