製品の概要

  • 製品名
  • 製品の詳細
    Chicken polyclonal to Fas Ligand
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    C terminal amino acids 191-355 of Human Fas Ligand

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab53282 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000. Predicted molecular weight: 38 kDa.

ターゲット情報

  • 機能
    Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.
  • 関連疾患
    Defects in FASLG are the cause of autoimmune lymphoproliferative syndrome type 1B (ALPS1B) [MIM:601859]; also known as Canale-Smith syndrome (CSS). ALPS is a childhood syndrome involving hemolytic anemia and thrombocytopenia with massive lymphadenopathy and splenomegaly.
  • 配列類似性
    Belongs to the tumor necrosis factor family.
  • 翻訳後修飾
    N-glycosylated.
    The soluble form derives from the membrane form by proteolytic processing.
  • 細胞内局在
    Cell membrane. Secreted. May be released into the extracellular fluid, probably by cleavage form the cell surface.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ALPS1B antibody
    • Apoptosis (APO 1) antigen ligand 1 antibody
    • Apoptosis antigen ligand 1 antibody
    • Apoptosis antigen ligand antibody
    • APT1LG1 antibody
    • APTL antibody
    • CD178 antibody
    • CD178 antigen antibody
    • CD95 ligand antibody
    • CD95-L antibody
    • CD95L antibody
    • CD95L protein antibody
    • Fas antigen ligand antibody
    • Fas L antibody
    • Fas ligand (TNF superfamily member 6) antibody
    • Fas ligand antibody
    • FASL antibody
    • Fasl Fas ligand (TNF superfamily member 6) antibody
    • FASLG antibody
    • Generalized lymphoproliferative disease antibody
    • Gld antibody
    • soluble form antibody
    • TNFL6_HUMAN antibody
    • TNFSF6 antibody
    • Tumor necrosis factor (ligand) superfamily member 6 antibody
    • Tumor necrosis factor ligand superfamily member 6 antibody
    see all

Anti-Fas Ligand antibody 画像

  • Anti-Fas Ligand antibody (ab53282) at 1/2000 dilution + E coli-derived fusion protein

    Secondary
    Goat anti-IgY-HRP at 1/1000 dilution

    Predicted band size : 38 kDa
    Observed band size : 74 kDa (why is the actual band size different from the predicted?)

プロトコール

Anti-Fas Ligand antibody (ab53282) 使用論文

ab53282 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab53282.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録