Goat polyclonal to FAPP2
, corresponding to C terminal amino acids 428-440 of Human FAPP2
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris saline, pH 7.3
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Immunogen affinity purified
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution. Preliminary experiments gave no signal but low background in Human Kidney and Testis lysates at up to 1µg/ml.
Use a concentration of 2 - 4 µg/ml. In paraffin embedded Human Placenta shows strong staining of cytoplasm in the margins of villi.
Involved in TGN-to-plasma membrane transport and in the formation of post-Golgi constitutive carriers. May play a role in ensuring the coordination of the budding and the fission reactions.
Expressed in kidney cell lines.
Contains 1 PH domain.
Interacts with PIP and ARF via plekstrin homology domain.
Cytoplasm. Localized to perinuclear structures in the trans-Golgi network.
Information by UniProt
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