製品の概要

  • 製品名Anti-FANCG antibody
    FANCG 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to FANCG
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    MSRQTTSVGSSC

    , corresponding to amino acids 1 - 12 of Human FANCG.

  • 特記事項Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of opening.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーpH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 0.424% Potassium phosphate, 0.878% Sodium chloride
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab5067 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500. Detects a band of approximately 69 kDa (predicted molecular weight: 69 kDa).

ターゲット情報

  • 機能DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.
  • 組織特異性Highly expressed in testis and thymus. Found in lymphoblasts.
  • 関連疾患Defects in FANCG are a cause of Fanconi anemia (FA) [MIM:227650]. FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.
  • 配列類似性Contains 4 TPR repeats.
  • 細胞内局在Nucleus. Cytoplasm. The major form is nuclear. The minor form is cytoplasmic.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DNA repair protein XRCC9 antibody
    • FAG antibody
    • FANCG antibody
    • FANCG_HUMAN antibody
    • Fanconi anaemia complementation group G antibody
    • Fanconi anemia group G protein antibody
    • Protein FACG antibody
    • X ray repair, complementing defective, in Chinese hamster cells 9 antibody
    • X-ray repair, complementing defective, in Chinese hamster, 9 antibody
    • XRCC9 antibody
    see all

Anti-FANCG antibody 画像

  • Anti-FANCG antibody (ab5067) at 1/500 dilution + HeLa whole cell lysate at 35 µg

    Secondary
    IRDye 800 conjugated Goat anti-Rabbit IgG [H&L] at 1/10000 dilution

    Performed under reducing conditions.

    Predicted band size : 69 kDa
    Observed band size : 69 kDa
    Additional bands at : 11 kDa,24 kDa. We are unsure as to the identity of these extra bands.

Anti-FANCG antibody (ab5067) 使用論文

ab5067 has not yet been referenced specifically in any publications.

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