Anti-FADD (phospho S194) 抗体 [EPR1816Y] (ab68475)

製品の概要

  • 製品名Anti-FADD (phospho S194) antibody [EPR1816Y]
    FADD 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR1816Y] to FADD (phospho S194)
  • アプリケーション適用あり: WB, IPmore details
    適用なし: Flow Cyt,ICC/IF or IHC-P
  • 種交差性
    交差種: Human
  • 免疫原

    A synthetic peptide corresponding to residues surrounding serine 194 of human FADD.

  • ポジティブ・コントロール
    • Jurkat cell lysate
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab68475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IP
  • 追加情報IP: 1/30.
    WB: 1/500. Detects a band of approximately 27 kDa (predicted molecular weight: 23 kDa).

    Is unsuitable for Flow Cyt, ICC/IF or IHC-P.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
    • 組織特異性Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.
    • 配列類似性Contains 1 death domain.
      Contains 1 DED (death effector) domain.
    • ドメインContains a death domain involved in the binding of the corresponding domain within Fas receptor.
    • Information by UniProt
    • 参照データベース
    • 別名
      • FADD antibody
      • FADD protein antibody
      • FADD_HUMAN antibody
      • Fas (TNFRSF6) associated via death domain antibody
      • Fas associated via death domain antibody
      • Fas associating death domain containing protein antibody
      • Fas associating protein antibody
      • Fas associating protein with death domain antibody
      • Fas TNFRSF6 associated via death domain antibody
      • FAS-associated death domain protein antibody
      • FAS-associating death domain-containing protein antibody
      • GIG 3 antibody
      • GIG3 antibody
      • Growth inhibiting gene 3 protein antibody
      • Growth-inhibiting gene 3 protein antibody
      • H sapiens mRNA for mediator of receptor induced toxicity antibody
      • Mediator of receptor induced toxicity antibody
      • MGC8528 antibody
      • MORT 1 antibody
      • MORT1 antibody
      • Protein FADD antibody
      see all

    Anti-FADD (phospho S194) antibody [EPR1816Y] 画像

    • All lanes : Anti-FADD (phospho S194) antibody [EPR1816Y] (ab68475) at 1/500 dilution

      Lane 1 : Jurkat cell lysate, untreated.
      Lane 2 : Jurkat cell lysate, treated with calyculin A.

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP conjugated Goat anti-Rabbit at 1/2000 dilution

      Predicted band size : 23 kDa
      Observed band size : 27 kDa (why is the actual band size different from the predicted?)

    Anti-FADD (phospho S194) antibody [EPR1816Y] (ab68475) 使用論文

    ab68475 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab68475.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"