Anti-Factor XIII/XIIIa 抗体 (ab45000)

製品の概要

  • 製品名Anti-Factor XIII/XIIIa antibody
    Factor XIII/XIIIa 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Factor XIII/XIIIa
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein corresponding to A-subunit of human coagulation Factor XIII.

  • ポジティブ・コントロール
    • Capillary hemangioma, dermatofibroma and placenta.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab45000 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Detects a band of approximately 160 kDa (un-reduced dimer) or 80kDa (reduced monomer).
IHC-P 1/2000.

ターゲット情報

  • 関連性Factor XIII is a beta globulin found in plasma and is composed of two subunits. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Factor XIII A is the catalytic subunit and is a dimmer of molecular weight 160kDa. The B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIII A, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
  • 細胞内局在Cytoplasmic in most tissues, but also secreted in the blood plasma
  • 参照データベース
  • 別名
    • Coagulation factor XIII A chain antibody
    • Coagulation factor XIII A chain precursor antibody
    • Coagulation factor XIII A polypeptide antibody
    • Coagulation factor XIII A1 polypeptide antibody
    • Coagulation factor XIII A1 subunit antibody
    • Coagulation factor XIIIa antibody
    • F13A antibody
    • F13A1 antibody
    • Factor XIIIA antibody
    • FXIIIA antibody
    • Protein glutamine gamma glutamyltransferase A chain antibody
    • TGase antibody
    • Transglutaminase A chain antibody
    see all

Anti-Factor XIII/XIIIa antibody (ab45000) 使用論文

ab45000 has not yet been referenced specifically in any publications.

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