製品の概要

  • 製品名Anti-Factor X antibody
    Factor X 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal to Factor X
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Full length native purified Mouse Factor X

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 50% (v/v)Glycerol/water
  • Concentration information loading...
  • 精製度Ion Exchange Chromatography
  • 特記事項(精製)Salt fractionation followed by gel filtration and ion exchange chromatography.
  • ポリ/モノモノクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab61389 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Predicted molecular weight: 55 kDa.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
  • 組織特異性Plasma; synthesized in the liver.
  • 関連疾患Defects in F10 are the cause of factor X deficiency (FA10D) [MIM:227600]. A hemorrhagic disease with variable presentation. Affected individuals can manifest prolonged nasal and mucosal hemorrhage, menorrhagia, hematuria, and occasionally hemarthrosis. Some patients do not have clinical bleeding diathesis.
  • 配列類似性Belongs to the peptidase S1 family.
    Contains 2 EGF-like domains.
    Contains 1 Gla (gamma-carboxy-glutamate) domain.
    Contains 1 peptidase S1 domain.
  • 翻訳後修飾The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.
    N- and O-glycosylated.
    The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway).
    The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 製品の状態Cleaved into the following 3 chains: 1. Factor X light chain 2. Factor X heavy chain 3. Activated factor Xa heavy chain
  • 別名
    • Activated factor Xa heavy chain antibody
    • Coagulation factor X antibody
    • F10 antibody
    • FA10_HUMAN antibody
    • factor Xa antibody
    • FX antibody
    • FXA antibody
    • Prothrombinase antibody
    • Stuart factor antibody
    • Stuart Prower factor antibody
    • Stuart-Prower factor antibody
    see all

Anti-Factor X antibody (ab61389) 使用論文

ab61389 has not yet been referenced specifically in any publications.

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Smearing could come from too much albumin and IgGs in the sample (these are inherent to plasma samples and dominate over other proteins in the plasma). Thus, removing those beforehand could help as well. There are columns commercially available specifi...

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