製品の概要

  • 製品名Anti-Factor V antibody [EPR5191]
    Factor V 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR5191] to Factor V
  • アプリケーション適用あり: Flow Cyt, WBmore details
    適用なし: ICC,IHC-P or IP
  • 種交差性
    交差種: Human
  • 免疫原

    A synthetic peptide corresponding to residues in the light chain of Human Factor V

  • ポジティブ・コントロール
    • Human plasma and platelet lysates
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファーPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 精製度Tissue culture supernatant
  • ポリ/モノモノクローナル
  • クローン名EPR5191
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab108614 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use at an assay dependent concentration. PubMed: 27492853
WB 1/1000 - 1/10000. Predicted molecular weight: 252 kDa.
  • 追加情報Is unsuitable for ICC,IHC-P or IP.
  • ターゲット情報

    • 機能Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin.
    • 組織特異性Plasma.
    • 関連疾患Factor V deficiency
      Thrombophilia due to activated protein C resistance
      Budd-Chiari syndrome
      Ischemic stroke
      Pregnancy loss, recurrent, 1
    • 配列類似性Belongs to the multicopper oxidase family.
      Contains 3 F5/8 type A domains.
      Contains 2 F5/8 type C domains.
      Contains 6 plastocyanin-like domains.
    • ドメインDomain B contains 35 x 9 AA tandem repeats, and 2 x 17 AA repeats.
    • 翻訳後修飾Thrombin activates factor V proteolytically to the active cofactor, factor Va (formation of a heavy chain at the N-terminus and a light chain at the C-terminus).
      Sulfation is required for efficient thrombin cleavage and activation and for full procoagulant activity.
      Activated protein C inactivates factor V and factor Va by proteolytic degradation.
      Phosphorylation sites are present in the extracellular medium.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Activated protein C cofactor antibody
      • APC cofactor antibody
      • coagulation factor V (proaccelerin, labile factor) antibody
      • Coagulation factor V antibody
      • coagulation factor V jinjiang A2 domain antibody
      • Coagulation factor V light chain antibody
      • F5 antibody
      • FA5_HUMAN antibody
      • Factor V Leiden antibody
      • FactorV antibody
      • FVL antibody
      • Labile factor antibody
      • PCCF antibody
      • Proaccelerin antibody
      • proaccelerin, labile factor antibody
      • Protein C cofactor antibody
      • RPRGL1 antibody
      • THPH2 antibody
      see all

    Anti-Factor V antibody [EPR5191] 画像

    • All lanes : Anti-Factor V antibody [EPR5191] (ab108614) at 1/1000 dilution

      Lane 1 : Human plasma lysate
      Lane 2 : Human platelet lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 252 kDa

    Anti-Factor V antibody [EPR5191] (ab108614) 使用論文

    This product has been referenced in:
    • Kaliberov SA  et al. Retargeted adenoviruses for radiation-guided gene delivery. Cancer Gene Ther N/A:N/A (2016). Flow Cyt ; Human . Read more (PubMed: 27492853) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab108614.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"