製品の概要

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservative: None
    Constituents: 50% Glycerol, HEPES-buffered saline, pH 7.5
  • 精製度Whole antiserum
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab30905 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent concentration.
WB Use at an assay dependent concentration.
IP Use at an assay dependent concentration.

ターゲット情報

  • 機能Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin.
  • 組織特異性Plasma.
  • 関連疾患Factor V deficiency
    Thrombophilia due to activated protein C resistance
    Budd-Chiari syndrome
    Ischemic stroke
    Pregnancy loss, recurrent, 1
  • 配列類似性Belongs to the multicopper oxidase family.
    Contains 3 F5/8 type A domains.
    Contains 2 F5/8 type C domains.
    Contains 6 plastocyanin-like domains.
  • ドメインDomain B contains 35 x 9 AA tandem repeats, and 2 x 17 AA repeats.
  • 翻訳後修飾Thrombin activates factor V proteolytically to the active cofactor, factor Va (formation of a heavy chain at the N-terminus and a light chain at the C-terminus).
    Sulfation is required for efficient thrombin cleavage and activation and for full procoagulant activity.
    Activated protein C inactivates factor V and factor Va by proteolytic degradation.
    Phosphorylation sites are present in the extracellular medium.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Activated protein C cofactor antibody
    • APC cofactor antibody
    • coagulation factor V (proaccelerin, labile factor) antibody
    • Coagulation factor V antibody
    • coagulation factor V jinjiang A2 domain antibody
    • Coagulation factor V light chain antibody
    • F5 antibody
    • FA5_HUMAN antibody
    • Factor V Leiden antibody
    • FactorV antibody
    • FVL antibody
    • Labile factor antibody
    • PCCF antibody
    • Proaccelerin antibody
    • proaccelerin, labile factor antibody
    • Protein C cofactor antibody
    • RPRGL1 antibody
    • THPH2 antibody
    see all

Anti-Factor V antibody (ab30905) 使用論文

ab30905 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab30905.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"