Anti-Factor D/CFD 抗体 [I8/1] (ab36383)
Key features and details
- Mouse monoclonal [I8/1] to Factor D/CFD
- Suitable for: ELISA, WB
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-Factor D/CFD antibody [I8/1]
Factor D/CFD 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [I8/1] to Factor D/CFD -
由来種
Mouse -
特異性
ab36383 is specific for complement Factor D/CFD in serum and plasma.
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アプリケーション
適用あり: ELISA, WBmore details -
種交差性
交差種: Human -
免疫原
Full length native protein (purified) corresponding to Human Factor D/CFD.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.097% Sodium azide
Constituents: 2.09% Sodium chloride, PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
I8/1 -
ミエローマ
x63-Ag8.653 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab36383の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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特記事項 |
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ELISA
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. -
関連疾患
Defects in CFD are the cause of complement factor D deficiency (CFD deficiency) [MIM:134350]. CFD deficiency predisposes to invasive meningococcal disease. -
配列類似性
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 1675 Human
- Omim: 134350 Human
- SwissProt: P00746 Human
- Unigene: 155597 Human
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別名
- Adipsin antibody
- Adipsin/complement factor D antibody
- Adn antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab36383 は論文での使用が確認できていません。