製品の概要

  • 製品名Anti-F Box G - Domain 3 antibody
    F Box G - Domain 3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to F Box G - Domain 3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 36-85 (CCYVSRRLSQ LSSHDPLWRR HCKKYWLISE EEKTQKNQCW KSLFIDTYSD) of Human FF Box G – Domain 3 protein (NP_208385).

  • ポジティブ・コントロール
    • Human fetal small intestine lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab90143 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 55 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
  • 配列類似性Contains 1 apaG domain.
    Contains 1 F-box domain.
  • 細胞内局在Nucleus. Colocalizes with PML at the peripheries of nuclear bodies.
  • Information by UniProt
  • 参照データベース
  • 別名
    • F box only protein 3 antibody
    • F box protein 3 antibody
    • F box protein FBX3 antibody
    • F-box only protein 3 antibody
    • FBA antibody
    • FBX3 antibody
    • FBX3_HUMAN antibody
    • FBXO3 antibody
    see all

Anti-F Box G - Domain 3 antibody 画像

  • Anti-F Box G - Domain 3 antibody (ab90143) at 1 µg/ml + Human fetal small intestine lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 55 kDa

Anti-F Box G - Domain 3 antibody (ab90143) 使用論文

ab90143 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"