Anti-Extracellular matrix protein 1 抗体 [COMPO2], prediluted (ab75232)

製品の概要

  • 製品名Anti-Extracellular matrix protein 1 antibody [COMPO2], prediluted
    Extracellular matrix protein 1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [COMPO2] to Extracellular matrix protein 1, prediluted
  • 特異性ab75232 Secretory Component is an epithelial transport receptor for polymeric IgA and IgM. Antibody to secretory component has been shown to be useful for identifying glandular carcinomas.
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Rat, Human
  • 免疫原

    Full length native protein (purified) corresponding to Human Secretory Component Glycoprotein. Semi- purified human secretory component.

  • ポジティブ・コントロール
    • Stomach, small intestine, colon carcinoma.
  • 特記事項Clone designation COMPO2 is the same as SC-05.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab75232 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/1.

ターゲット情報

  • 機能Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity.
  • 組織特異性Expressed in breast cancer tissues. Little or no expression observed in normal breast tissues. Expressed in skin; wide expression is observed throughout the dermis with minimal expression in the epidermis.
  • 関連疾患Defects in ECM1 are the cause of lipoid proteinosis (LiP) [MIM:247100]; also known as lipoid proteinosis of Urbach and Wiethe or hyalinosis cutis et mucosae. LiP is a rare autosomal recessive disorder characterized by generalized thickening of skin, mucosae and certain viscera. Classical features include beaded eyelid papules and laryngeal infiltration leading to hoarseness. Histologically, there is widespread deposition of hyaline material and disruption/reduplication of basement membrane.
  • 細胞内局在Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ECM 1 antibody
    • Ecm1 antibody
    • ECM1_HUMAN antibody
    • Extracellular matrix protein 1 antibody
    • Secretory component p85 antibody
    • URBWD antibody
    see all

Anti-Extracellular matrix protein 1 antibody [COMPO2], prediluted 画像

  • Formalin-fixed, paraffin-embedded human colon carcinoma stained with ab75232, using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.

Anti-Extracellular matrix protein 1 antibody [COMPO2], prediluted (ab75232) 使用論文

ab75232 has not yet been referenced specifically in any publications.

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