製品の概要

  • 製品名
    Exendin-4 (Exenatide)
  • 製品の詳細
    Potent GLP-1 receptor agonist
  • 別名
    • AC 2993
    • Exenatide
  • 生理活性の詳細
    High affinity glucagon-like peptide 1 (GLP-1) receptor agonist (Kd = 136 pM).
  • 精製度
    > 95%

製品の特性

参考文献

This product has been referenced in:
  • Thorens B  et al. Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor. Diabetes 42:1678-82 (1993). Read more (PubMed: 8405712) »
  • Malhotra R  et al. Exendin-4, a new peptide from Heloderma suspectum venom, potentiates cholecystokinin-induced amylase release from rat pancreatic acini. Regul Pept 41:149-56 (1992). Read more (PubMed: 1279756) »
  • Eng J  et al. Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. J Biol Chem 267:7402-5 (1992). Read more (PubMed: 1313797) »

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