製品の概要

  • 製品名Anti-EVER2 antibody
    EVER2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to EVER2
  • 特異性At least three isoforms of EVER2 are known to exist; this antibody will only recognize the two larger isoforms. The antibody has no cross reactivity to EVER1.
  • アプリケーション適用あり: ICC/IF, IHC-P, WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    A 14 amino acid synthetic peptide from near the center of human EVER2.

  • ポジティブ・コントロール
    • Jurkat cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab69859 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 82 kDa (predicted molecular weight: 82 kDa).Can be blocked with EVER2 peptide (ab169739).

ターゲット情報

  • 関連性Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc. At least two isoforms of EVER2 are known to exist.
  • 細胞内局在Endoplasmic reticulum membrane; Multi pass membrane protein.
  • 参照データベース
  • 別名
    • epidermodysplasia verruciformis 2 antibody
    • Epidermodysplasia verruciformis protein 2 antibody
    • EV2 antibody
    • EVIN2 antibody
    • FLJ40668 antibody
    • FLJ43684 antibody
    • MGC102701 antibody
    • MGC40121 antibody
    • TMC8 antibody
    • Transmembrane channel like protein 8 antibody
    see all

Anti-EVER2 antibody 画像

  • Lane 1 : Anti-EVER2 antibody (ab69859) at 1 µg/ml
    Lane 2 : Anti-EVER2 antibody (ab69859) at 2 µg/ml

    Lane 1 : Jurkat cell lysate
    Lane 2 : Jurkat cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 82 kDa
    Observed band size : 70,82 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 68 kDa. We are unsure as to the identity of these extra bands.
  • ab69859 at 5 µg/ml staining EVER2 in human brain tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).

  • Immunofluorescence of EVER2 in Human Brain cells using ab69859 at 20 ug/ml.

Anti-EVER2 antibody (ab69859) 使用論文

ab69859 has not yet been referenced specifically in any publications.

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Thank you for your inquiry.

Unfortunately, we are not able to release the immunogen sequence for ab67325 and ab69859 as it is proprietary information.

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Je suis désolée d'apprendre que ab69859 ne vous donne pas de bons résultats en Western blot.
Comme discuté au téléphone hier, j'avais contacté le laboratoire. Le laboratoire avait effectivement aussi vu des fois une bande additionnelle à 130+ kD d...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"