製品の概要

  • 製品名Anti-EVC2 antibody
    EVC2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to EVC2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to a sequence within amino acids 1246 - 1308 (LEPIGELAPV PIVGAETIDL LNTGEKLFIF RNPKEPEISL HVPPRKKKNF LNAKKAMRAL GMD) of Human EVC2 (NP_667338)

  • ポジティブ・コントロール
    • A431, H1299, HeLa and HepG2 cells

法規制情報

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab96296 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 148 kDa.

ターゲット情報

  • 関連性EVC2 is an integral membrane protein that plays a vital role in bone formation and skeletal development. Defects in EVC2 are a cause of Ellis-van Creveld syndrome (EVC), also known as chondroectodermal dysplasia. EVC is an autosomal recessive disorder characterized by the clinical tetrad of chondrodystrophy, polydactyly, ectodermal dysplasia and cardiac anomalies. Patients manifest short-limb dwarfism, short ribs, postaxial polydactyly and dysplastic nails and teeth. Congenital heart defects, most commonly an atrioventricular septal defect, are observed in 60% of affected individuals. Defects in Defects in EVC2 are also a cause of acrofacial dysostosis Weyers type (WAD), also known as Curry-Hall syndrome. Acrofacial dysostoses are a heterogeneous group of disorders combining limb defects with facial abnormalities. WAD is an autosomal dominant disorder characterized by dysplastic nails, postaxial polydactyly, acrofacial dysostosis, short limbs and short stature. The phenotype is milder than Ellis-van Creveld syndrome.
  • 細胞内局在Membrane; Multi-pass membrane protein
  • 参照データベース
  • 別名
    • Ellis van Creveld syndrome 2 antibody
    • LBN antibody
    • Limbin antibody

Anti-EVC2 antibody 画像

  • Anti-EVC2 antibody (ab96296) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

    Predicted band size : 148 kDa

Anti-EVC2 antibody (ab96296) 使用論文

ab96296 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Western blot
Sample Mouse Cell lysate - whole cell (MEF/primary chondrocyte)
Loading amount 80 µg
Specification MEF/primary chondrocyte
Gel Running Conditions Reduced Denaturing
Blocking step Milk as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: 25°C
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投稿 May 08 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"