製品の概要

  • 製品名Anti-EVA1 antibody
    EVA1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to EVA1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    synthetic peptide corresponding to a region within N terminal amino acids 35-84 (LEAVNGTDARLKCTFSSFAPVGDALTVTWNFRPLDGGPEQFVFYYHIDP F) of Human EVA1 (NP_005788)

  • ポジティブ・コントロール
    • OVCAR-3 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab98877 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 24 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 関連性Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. EVA1 is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. EVA1 expression is elevated in some T-cell leukemias. There are two isoforms.
  • 細胞内局在Cell Membrane; Single-pass type I membrane protein, cytoskeleton
  • 参照データベース
  • 別名
    • Epithelial V like antigen 1 antibody
    • EVA antibody
    • EVA1 antibody
    • MPZL2 antibody
    • MPZL2 myelin protein zero like 2 antibody
    • Myelin protein zero like 2 antibody
    • Myelin protein zero like protein 2 antibody
    see all

Anti-EVA1 antibody 画像

  • Anti-EVA1 antibody (ab98877) at 1 µg/ml + OVCAR-3 cell lysate at 10 µg

    Predicted band size : 24 kDa

Anti-EVA1 antibody (ab98877) 使用論文

ab98877 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"