製品の概要

  • 製品名Anti-ETHE1 antibody
    ETHE1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ETHE1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 92-141 (RSLLPGCQSV ISRLSGAQAD LHIEDGDSIR FGRFALETRA SPGHTPGCVT) of Human ETHE1 (NP_055112).

  • ポジティブ・コントロール
    • COLO205 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab108138 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 28 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Probably plays an important role in metabolic homeostasis in mitochondria. May function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm. Suppresses p53-induced apoptosis by preventing nuclear localization of RELA.
  • 組織特異性Ubiquitously expressed.
  • 関連疾患Defects in ETHE1 are a cause of ethylmalonic encephalopathy (EE) [MIM:602473]. EE is an autosomal recessive disorder characterized by neurodevelopmental delay and regression, recurrent petechiae, acrocyanosis, diarrhea, leading to death in the first decade of life. It is also associated with persistent lactic acidemia and ethylmalonic and methylsuccinic aciduria.
  • 配列類似性Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
  • 細胞内局在Cytoplasm. Nucleus. Mitochondrion matrix. According to PubMed:12398897, it is cytoplasmic and nuclear. According to PubMed:14732903, it is found in the mitochondrial matrix.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Ethe1 antibody
    • ETHE1 protein, mitochondrial precursor antibody
    • ETHE1_HUMAN antibody
    • ethylmalonic encephalopathy 1 antibody
    • Ethylmalonic encephalopathy protein 1 antibody
    • hepatoma subtracted clone one antibody
    • Hepatoma subtracted clone one protein antibody
    • HSCO antibody
    • mitochondrial antibody
    • Protein ETHE1 antibody
    • Protein ETHE1 mitochondrial antibody
    • YF13H12 antibody
    see all

Anti-ETHE1 antibody 画像

  • Anti-ETHE1 antibody (ab108138) at 1 µg/ml + COLO205 cell lysate at 10 µg

    Predicted band size : 28 kDa

Anti-ETHE1 antibody (ab108138) 使用論文

ab108138 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"