Anti-ESM1 抗体 (ab103590)
Key features and details
- Rabbit polyclonal to ESM1
- Suitable for: WB, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-ESM1 antibody
ESM1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to ESM1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, ICC/IFmore details -
種交差性
交差種: Mouse, Human -
免疫原
Recombinant full length protein within Human ESM1 aa 1-200. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab103590の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/1000. Predicted molecular weight: 20 kDa.
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ICC/IF | (2) |
Use at an assay dependent concentration.
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特記事項 |
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WB
1/500 - 1/1000. Predicted molecular weight: 20 kDa. |
ICC/IF
Use at an assay dependent concentration. |
ターゲット情報
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機能
May have potent implications in lung endothelial cell-leukocyte interactions. -
組織特異性
Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney. -
配列類似性
Contains 1 IGFBP N-terminal domain. -
翻訳後修飾
May contain intrachain disulfide bonds. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 11082 Human
- Entrez Gene: 71690 Mouse
- Omim: 601521 Human
- SwissProt: Q9NQ30 Human
- SwissProt: Q9QYY7 Mouse
- Unigene: 129944 Human
- Unigene: 38929 Mouse
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別名
- Endocan antibody
- Endothelial cell specific molecule 1 antibody
- Endothelial cell-specific molecule 1 antibody
see all
画像
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Anti-ESM1 antibody (ab103590) at 1/500 dilution + Human kidney tissue lysate at 50 µg
Predicted band size: 20 kDa -
All lanes : Anti-ESM1 antibody (ab103590) at 1/500 dilution
Lane 1 : ESM1 transfected 293T cell line lysate
Lane 2 : Non-transfected 293T cell line lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 20 kDa
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (14)
ab103590 は 14 報の論文で使用されています。
- Li YK et al. Validation of ESM1 Related to Ovarian Cancer and the Biological Function and Prognostic Significance. Int J Biol Sci 19:258-280 (2023). PubMed: 36594088
- Gu X et al. ESM1/HIF‑1α pathway modulates chronic intermittent hypoxia‑induced non‑small‑cell lung cancer proliferation, stemness and epithelial‑mesenchymal transition. Oncol Rep 45:1226-1234 (2021). PubMed: 33650648
- Choi HS et al. Anticancer Effect of Benzimidazole Derivatives, Especially Mebendazole, on Triple-Negative Breast Cancer (TNBC) and Radiotherapy-Resistant TNBC In Vivo and In Vitro. Molecules 26:N/A (2021). PubMed: 34500557
- Jin H & Kim HJ NK Cells Lose Their Cytotoxicity Function against Cancer Stem Cell-Rich Radiotherapy-Resistant Breast Cancer Cell Populations. Int J Mol Sci 22:N/A (2021). PubMed: 34502547
- Suzuki K et al. Recombinant Thrombomodulin Protects Against Lipopolysaccharide-induced Acute Respiratory Distress Syndrome Via Preservation of Pulmonary Endothelial Glycocalyx. Br J Pharmacol N/A:N/A (2020). PubMed: 32497259