製品の概要

  • 製品名Anti-ERp29 antibody
    ERp29 一次抗体 製品一覧
  • 製品の詳細
    Chicken polyclonal to ERp29
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to Human ERp29 aa 33-261 (C terminal).

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab37850 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: 1/2000. Predicted molecular weight of non-fusion protein: 29 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性Proper protein folding and post-translational modifications are essential for secretory protein export out of the endoplasmic reticulum. This task is accomplished by chaperone proteins such as protein disulfide isomerase (PDI), GRP94, and BiP. A recently characterized protein, designated ERp29, is closely related to these chaperone proteins and appears to be upregulated during ER stress conditions. ERp29 is a soluble 259-residue protein that is localized to the lumen of the endoplasmic reticulum in all mammalian cells. Research has shown that there are two primary domains within ERp29. The first is the C-terminal region that is a novel, all helical, fold that is most likely involved with ERp29 retention to the ER. The second is the N-terminal region that resembles that of PDI’s thioredoxin module. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER.
    • 細胞内局在Endoplasmic reticulum, Cell surface.
    • 参照データベース
    • 別名
      • C12orf8 antibody
      • Chromosome 12 open reading frame 8 antibody
      • Endoplasmic reticulum lumenal protein ERp28 antibody
      • Endoplasmic reticulum protein 29 antibody
      • Endoplasmic reticulum protein 29 isoform 1 antibody
      • Endoplasmic reticulum protein ERp29 antibody
      • Endoplasmic reticulum resident protein 28 antibody
      • Endoplasmic reticulum resident protein 29 antibody
      • Endoplasmic reticulum resident protein 31 antibody
      • ERp28 antibody
      • ERP29_HUMAN antibody
      • ERp31 antibody
      • PDI-DB antibody
      • PDIA9 antibody
      • Protein disulfide isomerase family A member 9 antibody
      see all

    Anti-ERp29 antibody 画像

    • Anti-ERp29 antibody (ab37850) at 1/2000 dilution + E. coli-derived fusion protein.

      Secondary
      Goat anti-IgY-HRP at 1/1000

      Predicted band size : 29 kDa
      Observed band size : 75 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 40 kDa (possible non-specific binding,degradation product),45 kDa (possible non-specific binding,degradation product),60 kDa (possible non-specific binding,degradation product).

    Anti-ERp29 antibody (ab37850) 使用論文

    ab37850 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab37850.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"