製品の概要

  • 製品名Anti-EREG antibody [MM0265- 12Y4]
    EREG 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MM0265- 12Y4] to EREG
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length Human EREG protein.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)The IgG fraction of culture supernatant was purified by Protein G affinity chromatography.
  • ポリ/モノモノクローナル
  • クローン名MM0265- 12Y4
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab89291 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 19 kDa.

ターゲット情報

  • 機能May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis.
  • 組織特異性In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon.
  • 配列類似性Contains 1 EGF-like domain.
  • 細胞内局在Cell membrane and Secreted > extracellular space.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Epiregulin antibody
    • EPR antibody
    • ER antibody
    • Ereg antibody
    • EREG_HUMAN antibody
    • Proepiregulin antibody
    see all

Anti-EREG antibody [MM0265- 12Y4] (ab89291) 使用論文

This product has been referenced in:
  • Oliveras-Ferraros C  et al. Cross-suppression of EGFR ligands amphiregulin and epiregulin and de-repression of FGFR3 signalling contribute to cetuximab resistance in wild-type KRAS tumour cells. Br J Cancer 106:1406-14 (2012). Read more (PubMed: 22491422) »

See 1 Publication for this product

Product Wall

Thank you for your reply. If the white band you are seeing on the darker background is at a molecular weight of 19 kDa, then it is the specific band of interest. The band can show up lighter than the background when the signal is too strong and the ECL...

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Thank you for contacting us. I am sorry this antibody is not giving good results in WB. Can you please provide some additional details of your experiment?

1) What type of samples were you testing and how were they prepared (lysis buffer, prot...

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Thank you for contacting us and your interest in our products. We have several antibodies directed against amphiregulin and epiregulin, however, as discussed over the phone, none have as yet been tested in IHC.

This does not mean that they wo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"