Anti-ERCC1 抗体 [SPM243], prediluted (ab54240)

製品の概要

  • 製品名Anti-ERCC1 antibody [SPM243], prediluted
    ERCC1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [SPM243] to ERCC1, prediluted
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat
  • 免疫原

    Recombinant full length protein (Human)

  • ポジティブ・コントロール
    • A431 or HeLa cells, or tonsil tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab54240 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: Ready-to-use, for 30 min at RT.
    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair.
    • 関連疾患Defects in ERCC1 are the cause of cerebro-oculo-facio-skeletal syndrome type 4 (COFS4) [MIM:610758]. COFS is a degenerative autosomal recessive disorder of prenatal onset affecting the brain, eye and spinal cord. After birth, it leads to brain atrophy, hypoplasia of the corpus callosum, hypotonia, cataracts, microcornea, optic atrophy, progressive joint contractures and growth failure. Facial dysmorphism is a constant feature. Abnormalities of the skull, eyes, limbs, heart and kidney also occur.
    • 配列類似性Belongs to the ERCC1/RAD10/SWI10 family.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • COFS 4 antibody
      • COFS4 antibody
      • DNA excision repair protein ERCC 1 antibody
      • DNA excision repair protein ERCC-1 antibody
      • DNA excision repair protein ERCC1 antibody
      • ERCC 1 antibody
      • ERCC1 antibody
      • ERCC1_HUMAN antibody
      • Excision repair cross complementation group 1 antibody
      • Excision repair cross complementing 1 antibody
      • Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1 antibody
      • Excision repair protein antibody
      • RAD 10 antibody
      • RAD10 antibody
      • UV 20 antibody
      • UV20 antibody
      see all

    Anti-ERCC1 antibody [SPM243], prediluted 画像

    • Ab54240 staining human ERCC1 in human tonsil tissue by immunohistochemistry using formalin fixed, paraffin embedded tissue.

    Anti-ERCC1 antibody [SPM243], prediluted (ab54240) 使用論文

    ab54240 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab54240.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"