製品の概要

  • 製品名Anti-ERCC1 antibody
    ERCC1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ERCC1
  • アプリケーション適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant Human ERCC1 protein.

  • ポジティブ・コントロール
    • Human lung small cell carcinoma and rectal carcinoma tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab93960 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB Use at an assay dependent concentration.

ターゲット情報

  • 機能Structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair.
  • 関連疾患Defects in ERCC1 are the cause of cerebro-oculo-facio-skeletal syndrome type 4 (COFS4) [MIM:610758]. COFS is a degenerative autosomal recessive disorder of prenatal onset affecting the brain, eye and spinal cord. After birth, it leads to brain atrophy, hypoplasia of the corpus callosum, hypotonia, cataracts, microcornea, optic atrophy, progressive joint contractures and growth failure. Facial dysmorphism is a constant feature. Abnormalities of the skull, eyes, limbs, heart and kidney also occur.
  • 配列類似性Belongs to the ERCC1/RAD10/SWI10 family.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • COFS 4 antibody
    • COFS4 antibody
    • DNA excision repair protein ERCC 1 antibody
    • DNA excision repair protein ERCC-1 antibody
    • DNA excision repair protein ERCC1 antibody
    • ERCC 1 antibody
    • ERCC1 antibody
    • ERCC1_HUMAN antibody
    • Excision repair cross complementation group 1 antibody
    • Excision repair cross complementing 1 antibody
    • Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1 antibody
    • Excision repair protein antibody
    • RAD 10 antibody
    • RAD10 antibody
    • UV 20 antibody
    • UV20 antibody
    see all

Anti-ERCC1 antibody 画像

  • ab93960 at 1/100 dilution staining ERCC1 in formalin-fixed, paraffin-embedded Human lung small cell carcinoma tissue.
  • Anti-ERCC1 antibody (ab93960) at 1/100 dilution + lysate prepared from HeLa cells

Anti-ERCC1 antibody (ab93960) 使用論文

ab93960 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"