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RabMAb

Anti-EPS8 抗体 [EPR6112] (ab124882)

製品の概要

  • 製品名
    Anti-EPS8 antibody [EPR6112]
    EPS8 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR6112] to EPS8
  • アプリケーション
    適用あり: WB, IHC-P, ICC/IFmore details
    適用なし: Flow Cyt or IP
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to residues near the N-terminus of Human EPS8.

  • ポジティブ・コントロール
    • HeLa, A375, 293T, and K562 cell lysates, Human kidney tissue
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファー
    PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 精製度
    Tissue culture supernatant
  • ポリ/モノ
    モノクローナル
  • クローン名
    EPR6112
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab124882 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Detects a band of approximately 97 kDa (predicted molecular weight: 92 kDa).
IHC-P 1/100 - 1/250. antigen retrieval is recommended.
ICC/IF 1/50 - 1/100.
  • 追加情報
    Is unsuitable for Flow Cyt or IP.
  • ターゲット情報

    • 機能
      Upon binding to EGF receptor enhances EGF-dependent mitogenic signals. Can bind multiple cellular targets.
    • 組織特異性
      Expressed in all tissues analyzed, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Expressed in all epithelial and fibroblastic lines examined and in some, but not all, hematopoietic cells.
    • 配列類似性
      Belongs to the EPS8 family.
      Contains 1 PH domain.
      Contains 1 SH3 domain.
    • ドメイン
      The SH3 domain mediates interaction with SHB.
    • 翻訳後修飾
      Phosphorylated by several receptor tyrosine kinases.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Epidermal growth factor receptor kinase substrate 8 antibody
      • Epidermal growth factor receptor pathway substrate 8 antibody
      • EPS 8 antibody
      • EPS8 antibody
      • EPS8_HUMAN antibody
      see all

    Anti-EPS8 antibody [EPR6112] 画像

    • All lanes : Anti-EPS8 antibody [EPR6112] (ab124882) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : A375 cell lysate
      Lane 3 : 293T cell lysate
      Lane 4 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 92 kDa
    • Staining of EPS8 in Paraffin-embedded Human kidney tissue by Immunohistochemistry using ab124882 at a dilution of 1/100.

    Anti-EPS8 antibody [EPR6112] (ab124882) 使用論文

    This product has been referenced in:
    • Lu H  et al. Identification of HLA-A*1101-restricted cytotoxic T lymphocyte epitopes derived from epidermal growth factor pathway substrate number 8. Mol Med Rep 14:4999-5006 (2016). WB ; Human . Read more (PubMed: 27840923) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab124882.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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