Anti-Eph receptor A2+A3+A4 (phospho Y588 + Y596) 抗体 (ab62256)
Key features and details
- Rabbit polyclonal to Eph receptor A2+A3+A4 (phospho Y588 + Y596)
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Eph receptor A2+A3+A4 (phospho Y588 + Y596) antibody
Eph receptor A2+A3+A4 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Eph receptor A2+A3+A4 (phospho Y588 + Y596) -
由来種
Rabbit -
アプリケーション
適用あり: ICC/IFmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse -
免疫原
Synthetic peptide corresponding to Human Eph receptor A2+A3+A4 aa 550-650 (phospho Y588 + Y596).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab62256 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab62256の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ICC/IF | (1) |
1/500 - 1/1000.
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特記事項 |
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ICC/IF
1/500 - 1/1000. |
ターゲット情報
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関連性
Eph receptor A2 is the receptor for members of the ephrin-A family. It binds to ephrin-A1, -A3, -A4 and -A5. Eph receptor A3 is also a receptor for members of the ephrin-A family. It binds to ephrin-A2, -A3, -A4 and -A5 and is thought to play a role in lymphoid function. Eph receptor A4 is a receptor for members of the ephrin-A family. It binds to ephrin-A1, -A4 and -A5. It binds more poorly to ephrin-A2 and -A3. It may play a role in a signal transduction process involved in hindbrain pattern formation. -
細胞内局在
Cell Membrane -
参照データベース
- Entrez Gene: 1969 Human
- Entrez Gene: 2042 Human
- Entrez Gene: 2043 Human
- Entrez Gene: 13836 Mouse
- Entrez Gene: 13837 Mouse
- Entrez Gene: 13838 Mouse
- SwissProt: P29317 Human
- SwissProt: P29320 Human
see all -
別名
- ECK antibody
- EPH Receptor A2 antibody
- EPH Receptor A3 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (6)
ab62256 は 6 報の論文で使用されています。
- Lewis AE et al. Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting. Cell Rep 38:110510 (2022). PubMed: 35294885
- Valenzuela JI & Perez F Localized Intercellular Transfer of Ephrin-As by Trans-endocytosis Enables Long-Term Signaling. Dev Cell 52:104-117.e5 (2020). PubMed: 31866204
- Mansour M et al. PTP-PEST controls EphA3 activation and ephrin-induced cytoskeletal remodelling. J Cell Sci 129:277-89 (2016). WB ; Human . PubMed: 26644181
- Neill T et al. EphA2 is a functional receptor for the growth factor progranulin. J Cell Biol 215:687-703 (2016). PubMed: 27903606
- Sabet O et al. Ubiquitination switches EphA2 vesicular traffic from a continuous safeguard to a finite signalling mode. Nat Commun 6:8047 (2015). PubMed: 26292967
- Sharonov GV et al. Point mutations in dimerization motifs of the transmembrane domain stabilize active or inactive state of the EphA2 receptor tyrosine kinase. J Biol Chem 289:14955-64 (2014). ICC/IF ; Human . PubMed: 24733396