製品の概要

  • 製品名Anti-EPCR/CD201 antibody [RCR-379]
    EPCR/CD201 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [RCR-379] to EPCR/CD201
  • アプリケーション適用あり: IHC-Fr, Functional Studies, Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Tail base human EPCR positive RE1 cells

  • 特記事項


    ab81711 is useful for the inhibition of biological activity. The antibody inhibits thrombin dependent protein C activation and blocks APC mediated signalling.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab81711 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr 1/10 - 1/50.
Functional Studies 1/5 - 1/50.
Flow Cyt 1/10 - 1/50. ab18450-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
  • 組織特異性Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney.
  • 翻訳後修飾N-glycosylated.
    A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Activated protein C receptor antibody
    • APC receptor antibody
    • APCR antibody
    • bA42O4.2 antibody
    • CCCA antibody
    • CCD41 antibody
    • CD201 antibody
    • CD201 antigen antibody
    • cell cycle, centrosome-associated protein antibody
    • Cell cycle, centrosome-associated protein antibody
    • centrocyclin antibody
    • Endothelial cell protein C receptor antibody
    • Endothelial protein C receptor antibody
    • EPCR antibody
    • EPCR_HUMAN antibody
    • MGC23024 antibody
    • PROCR antibody
    • Protein C receptor, endothelial antibody
    see all

Anti-EPCR/CD201 antibody [RCR-379] (ab81711) 使用論文

This product has been referenced in:
  • Navarro S  et al. Association of the Thrombomodulin Gene c.1418C>T Polymorphism With Thrombomodulin Levels and With Venous Thrombosis Risk. Arterioscler Thromb Vasc Biol N/A:N/A (2013). Blocking ; Human . Read more (PubMed: 23520161) »

See 1 Publication for this product

Product Wall

Thanks for your email. I'm very sorry that even the replacement antibody still does not appear to be working as expected.

To help improve your results, Iam happy to provide a replacement of any primary antibody, credit or refund. Please let m...

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Thank you very much for your interest in ab81711. FuncS refers to this antibody's ability to inhibit the biological activity of EPCR. Unfortunately, all of the data we have for this clone is currently available on the online datasheet.

Becau...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"