製品の概要

  • 製品名Anti-EPB42 antibody
    EPB42 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to EPB42
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 448-497 (ISTKGVGSDR CEDITQNYKY PEGSLQEKEV LERVEKEKME REKDNGIRPP) of Human EPB42 (NP_000110).

  • ポジティブ・コントロール
    • Fetal liver lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab105076 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 80 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Probably plays an important role in the regulation of erythrocyte shape and mechanical properties.
  • 関連疾患Defects in EPB42 are the cause of spherocytosis type 5 (SPH5) [MIM:612690]; also known as hereditary spherocytosis type 5 (HS5). Spherocytosis is a hematologic disorder leading to chronic hemolytic anemia and characterized by numerous abnormally shaped erythrocytes which are generally spheroidal. Absence of band 4.2 associated with spur or target erythrocytes has also been reported.
  • 配列類似性Belongs to the transglutaminase superfamily. Transglutaminase family.
  • 翻訳後修飾Both cAMP-dependent kinase (CAPK) and another kinase present in the red-blood cells seem to be able to phosphorylate EPB42.
  • 細胞内局在Cell membrane. Cytoplasm > cytoskeleton. Cytoplasmic surface of erythrocyte membranes.
  • Information by UniProt
  • 参照データベース
  • 別名
    • EPB42 antibody
    • EPB42_HUMAN antibody
    • Erythrocyte membrane protein band 4.2 antibody
    • Erythrocyte protein 4.2 antibody
    • Erythrocyte surface protein band 4.2 antibody
    • MGC116735 antibody
    • MGC116737 antibody
    • P4.2 antibody
    • PA antibody
    • SPH5 antibody
    see all

Anti-EPB42 antibody 画像

  • Anti-EPB42 antibody (ab105076) at 5 µg/ml + Human fetal liver lysate at 10 µg

    Predicted band size : 80 kDa

Anti-EPB42 antibody (ab105076) 使用論文

ab105076 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"