製品の概要

  • 製品名Anti-ENTPD5 antibody
    ENTPD5 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ENTPD5
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 85-134 (SVKPGLSAFV DQPKQGAETV QGLLEVAKDS IPRSHWKKTP VVLKATAGLR) of Human ENTPD5 (NP_001240).

  • ポジティブ・コントロール
    • HT1080 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab118660 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
  • 組織特異性Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues.
  • パスウェイProtein modification; protein glycosylation.
  • 配列類似性Belongs to the GDA1/CD39 NTPase family.
  • 翻訳後修飾N-glycosylated; high-mannose type.
  • 細胞内局在Endoplasmic reticulum lumen.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD39 like 4 antibody
    • AI196558 antibody
    • AI987697 antibody
    • CD39 antigen like 4 antibody
    • CD39 antigen-like 4 antibody
    • CD39 like 4 antibody
    • CD39L4 antibody
    • Ectonucleoside triphosphate diphosphohydrolase 5 antibody
    • ENTP5_HUMAN antibody
    • Entpd5 antibody
    • ER UDPase antibody
    • ER-UDPase antibody
    • GDPase ENTPD5 antibody
    • Guanosine-diphosphatase ENTPD5 antibody
    • MGC163357 antibody
    • MGC163359 antibody
    • mNTPase antibody
    • NTPDase 5 antibody
    • Nucleoside diphosphatase antibody
    • PCPH antibody
    • Pcph proto oncogene protein antibody
    • Proto oncogene CPH antibody
    • UDPase ENTPD5 antibody
    • Uridine-diphosphatase ENTPD5 antibody
    see all

Anti-ENTPD5 antibody 画像

  • Anti-ENTPD5 antibody (ab118660) at 1 µg/ml + HT1080 cell lysate at 10 µg

    Predicted band size : 48 kDa

Anti-ENTPD5 antibody (ab118660) 使用論文

ab118660 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"