製品の概要

  • 製品名Anti-Enterokinase antibody
    Enterokinase 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Enterokinase
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性

    交差が予測される動物種: Horse, Cow, Pig
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 950 to the C-terminus of Human Enterokinase.

  • ポジティブ・コントロール
    • In IHC, this antibody gave a positive signal in a human duodenum formalin fixed paraffin embedded tissue section.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS
    Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab79974 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
  • 組織特異性Intestinal brush border.
  • 関連疾患Defects in TMPRSS15 are a cause of enterokinase deficiency (ENTKD) [MIM:226200]; a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive.
  • 配列類似性Belongs to the peptidase S1 family.
    Contains 2 CUB domains.
    Contains 2 LDL-receptor class A domains.
    Contains 1 MAM domain.
    Contains 1 peptidase S1 domain.
    Contains 1 SEA domain.
    Contains 1 SRCR domain.
  • 翻訳後修飾The chains are derived from a single precursor that is cleaved by a trypsin-like protease.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • PRSS 7 antibody
    • PRSS7 antibody
    • Enterokinase antibody
    • Enterokinase catalytic subunit antibody
    • Enteropeptidase antibody
    • Enteropeptidase catalytic light chain antibody
    • Enteropeptidase non catalytic heavy chain antibody
    • ENTK antibody
    • ENTK_HUMAN antibody
    • PROENTEROKINASE antibody
    • protease, serine, 7 (enterokinase) antibody
    • PRSS7 antibody
    • Serine protease 7 antibody
    • TMPRSS15 antibody
    • Transmembrane protease serine 15 antibody
    see all

Anti-Enterokinase antibody 画像

  • IHC image of Enterokinase staining in human duodenum formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab79974, 10µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

     For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Enterokinase antibody (ab79974) 使用論文

ab79974 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"