製品の概要

  • 製品名Anti-Ensconsin antibody
    Ensconsin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Ensconsin
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Cow, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 720-749 of Human Ensconsin (NP_003971.1).

  • ポジティブ・コントロール
    • Colon Carcinoma, Ovarian Carcinoma.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab99259 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/100 - 1/500. Antigen retrieval is recommended. Antigen retrieval with citrate buffer will enhance staining. Likely to work with frozen sections.

ターゲット情報

  • 機能Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments.
  • 組織特異性Expressed in the skin and cells of epithelial origin. Predominantly expressed in the suprabasal layers of the normal epidermis and relatively abundant in squamous cell carcinomas but barely detectable in basal cell carcinomas.
  • 配列類似性Belongs to the MAP7 family.
  • 翻訳後修飾The association with microtubules is regulated by phosphorylation during the cell cycle. During interphase only phosphorylated on serine. Phosphorylated on threonine in mitosis.
  • 細胞内局在Cytoplasm > perinuclear region. Basolateral cell membrane. Cytoplasm > cytoskeleton. Colocalized on microtubules. An intracellular redistribution is triggered during induction of keratinocyte terminal differentiation from microtubules with a perinuclear localization to cortical microtubules organized in spike-like bundles facing intercellular contacts.
  • Information by UniProt
  • 参照データベース
  • 別名
    • dJ325F22.2 (microtubule-associated protein 7 (EMAP115, E-MAP- 115)) antibody
    • E MAP 115 antibody
    • E-MAP-115 antibody
    • EMAP115 antibody
    • Ensconsin antibody
    • Epithelial microtubule associated protein of 115 kDa antibody
    • Epithelial microtubule-associated protein of 115 kDa antibody
    • MAP 7 antibody
    • MAP-7 antibody
    • Map7 antibody
    • MAP7_HUMAN antibody
    • Microtubule associated protein 7 antibody
    • Microtubule-associated protein 7 antibody
    see all

Anti-Ensconsin antibody 画像

  • ab99259 at 1/250 dilution staining Ensconsin in formalin-fixed, parrafin-embedded section of Human colon carcinoma by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Detection utilised DAB.

Anti-Ensconsin antibody (ab99259) 使用論文

ab99259 has not yet been referenced specifically in any publications.

Product Wall

DISCOUNT CODE: **********
Expiration date: ********

I am very pleased to hear you would like to accept our offer and test ab99259 in rat tissue. This code will give you 1 free PRIMARY ANTIBODY before the expiration date. To redeem this ...

Read More

Code de remise : *****
Date d’expiration : JJ MM AAAA

Je suis ravi que vous souhaitiez participer à notre offre et tester l'anti-Ensconsin ab99259 en ICC/IF et chez la souris. Le code de réduction correspondant est ***...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"