製品の概要

  • 製品名Anti-Ensconsin antibody
    Ensconsin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Ensconsin
  • アプリケーション適用あり: IHC-P, IPmore details
    適用なし: WB
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region between residue 150 and 200 of human Ensconsin (NP_003971.1).

  • ポジティブ・コントロール
    • Whole cell lysate from HeLa cells.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab80416 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/500 - 1/2000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
IP Use at 2-5 µg/mg of lysate.
  • 追加情報Is unsuitable for WB.
  • ターゲット情報

    • 機能Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments.
    • 組織特異性Expressed in the skin and cells of epithelial origin. Predominantly expressed in the suprabasal layers of the normal epidermis and relatively abundant in squamous cell carcinomas but barely detectable in basal cell carcinomas.
    • 配列類似性Belongs to the MAP7 family.
    • 翻訳後修飾The association with microtubules is regulated by phosphorylation during the cell cycle. During interphase only phosphorylated on serine. Phosphorylated on threonine in mitosis.
    • 細胞内局在Cytoplasm > perinuclear region. Basolateral cell membrane. Cytoplasm > cytoskeleton. Colocalized on microtubules. An intracellular redistribution is triggered during induction of keratinocyte terminal differentiation from microtubules with a perinuclear localization to cortical microtubules organized in spike-like bundles facing intercellular contacts.
    • Information by UniProt
    • 参照データベース
    • 別名
      • dJ325F22.2 (microtubule-associated protein 7 (EMAP115, E-MAP- 115)) antibody
      • E MAP 115 antibody
      • E-MAP-115 antibody
      • EMAP115 antibody
      • Ensconsin antibody
      • Epithelial microtubule associated protein of 115 kDa antibody
      • Epithelial microtubule-associated protein of 115 kDa antibody
      • MAP 7 antibody
      • MAP-7 antibody
      • Map7 antibody
      • MAP7_HUMAN antibody
      • Microtubule associated protein 7 antibody
      • Microtubule-associated protein 7 antibody
      see all

    Anti-Ensconsin antibody 画像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon carcinoma tissue labelling Ensconsin with ab80416 at 1/1000 (1µg/ml). Detection: DAB.

    Anti-Ensconsin antibody (ab80416) 使用論文

    ab80416 has not yet been referenced specifically in any publications.

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