製品の概要

  • 製品名Anti-Endostatin antibody
    Endostatin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Endostatin
  • アプリケーション適用あり: IHC-P, ICC/IF, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide conjugated to KLH, from the internal region of Human Endostatin (NP_085059.2).

  • ポジティブ・コントロール
    • Human breast collagen tissue; A549 cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab119279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 10 µg/ml.
ICC/IF 1/100 - 1/500.
ELISA 1/5000.

ターゲット情報

  • 機能COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.
    Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.
  • 組織特異性Present in multiple organs with highest levels in liver, lung and kidney.
  • 関連疾患Defects in COL18A1 are a cause of Knobloch syndrome (KNO) [MIM:267750]. KNO is an autosomal recessive disorder defined by the occurrence of high myopia, vitreoretinal degeneration with retinal detachment, macular abnormalities and occipital encephalocele.
  • 配列類似性Belongs to the multiplexin collagen family.
    Contains 1 FZ (frizzled) domain.
    Contains 1 TSP N-terminal (TSPN) domain.
  • 翻訳後修飾Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
  • 細胞内局在Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Alpha 1 collagen type 18 (XVIII)(COL18A1) antibody
    • Alpha 1 type XVIII collagen antibody
    • Antiangiogenic agent antibody
    • COIA1_HUMAN antibody
    • COL15A1 antibody
    • Col18a1 antibody
    • Collagen alpha 1(XV) chain antibody
    • Collagen alpha 1(XVIII) chain antibody
    • Collagen alpha-1(XV) chain antibody
    • Collagen type XV proteoglycan antibody
    • Collagen type XVIII alpha 1 antibody
    • Collagen XV, alpha 1 polypeptide antibody
    • Collagen, type XV, alpha 1 antibody
    • Endostatin antibody
    • Endostatin XV antibody
    • FLJ27325 antibody
    • FLJ34914 antibody
    • FLJ38566 antibody
    • KNO antibody
    • KNO1 antibody
    • KS antibody
    • MGC74745 antibody
    • Multi functional protein MFP antibody
    • OTTHUMP00000021782 antibody
    • OTTHUMP00000115472 antibody
    • OTTHUMP00000115473 antibody
    see all

Anti-Endostatin antibody 画像

  • ab119279, at 10 ug/ml, staining Endostatin in formalin-fixed, paraffin-embedded Human breast collagen tissue by Immunohistochemistry.
  • ab119279, at a 1/100 dilution, staining Endostatin in A549 cells by Immunofluorescence. The right image is treated with the synthesized peptide.

Anti-Endostatin antibody (ab119279) 使用論文

ab119279 has not yet been referenced specifically in any publications.

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