Anti-EMX2 抗体 (ab94713)

製品の概要

• 製品名
  Anti-EMX2 antibody
  EMX2 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to EMX2
• アプリケーション
  適用あり: WB, ICC/IFmore details
• 種交差性
  交差種: Mouse
  交差が予測される動物種: Rat, Chicken, Cow, Dog, Human, Pig, Zebrafish
• 免疫原

  Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Mouse EMX2.

  Immunogen の所有権に関して

  (Peptide available as ab109642.)

• ポジティブ･コントロール
  • This antibody gave a positive signal in both Mouse brain and hippocampus tissue lysates.

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• バッファー
  Preservative: 0.02% Sodium Azide
  Constituents: 1% BSA, PBS. pH 7.4
• Concentration information loading...
• 精製度
  Immunogen affinity purified
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 研究分野
  • Neuroscience
  • Cell Type Marker
  • Neural Stem Cell marker

  • Neuroscience
  • Neurology process
  • Neural Signal Transduction

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

アプリケーション

ターゲット情報

• 機能
  Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
• 組織特異性
  Cerebral cortex.
• 関連疾患
  Defects in EMX2 are the cause of schizencephaly (SCHZC) [MIM:269160]. Schizencephaly is an extremely rare human congenital disorder characterized by a full-thickness cleft within the cerebral hemispheres. These clefts are lined with gray matter and most commonly involve the parasylvian regions. Large portions of the cerebral hemispheres may be absent and replaced by cerebro-spinal fluid.
• 配列類似性
  Belongs to the EMX homeobox family.
  Contains 1 homeobox DNA-binding domain.
• 細胞内局在
  Nucleus.

• Target information above from: UniProt accession Q04743 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 523601 Cow
  • Entrez Gene: 2018 Human
  • Entrez Gene: 13797 Mouse
  • Entrez Gene: 499380 Rat
  • Omim: 600035 Human
  • SwissProt: Q17R00 Cow
  • SwissProt: Q04743 Human
  • SwissProt: Q04744 Mouse

  • Unigene: 202095 Human
  • Unigene: 245394 Mouse
  • Unigene: 16276 Rat

  see all
• 別名
  • Empty spiracles homeobox 2 antibody
  • Empty spiracles homolog 2 (Drosophila) antibody
  • Empty spiracles homolog 2 antibody

  • Empty spiracles like protein 2 antibody
  • Empty spiracles-like protein 2 antibody
  • EMX 2 antibody
  • EMX2 antibody
  • EMX2_HUMAN antibody
  • Homeobox protein EMX 2 antibody
  • Homeobox protein EMX2 antibody

  see all

プロトコール

• Western blot protocols
• Immunocytochemistry & immunofluorescence protocols