製品の概要
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製品名Anti-EMX2 antibody
EMX2 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to EMX2
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由来種Rabbit
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アプリケーション適用あり: WB, ICC/IFmore details
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種交差性交差種: Mouse
交差が予測される動物種: Rat, Chicken, Cow, Dog, Human, Pig, Zebrafish
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免疫原
Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Mouse EMX2.
(Peptide available as ab109642.)
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ポジティブ･コントロール
- This antibody gave a positive signal in both Mouse brain and hippocampus tissue lysates.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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バッファーPreservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS. pH 7.4 -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab94713 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 28 kDa). | |
| ICC/IF | Use at an assay dependent concentration. |
ターゲット情報
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機能Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
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組織特異性Cerebral cortex.
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関連疾患Defects in EMX2 are the cause of schizencephaly (SCHZC) [MIM:269160]. Schizencephaly is an extremely rare human congenital disorder characterized by a full-thickness cleft within the cerebral hemispheres. These clefts are lined with gray matter and most commonly involve the parasylvian regions. Large portions of the cerebral hemispheres may be absent and replaced by cerebro-spinal fluid.
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配列類似性Belongs to the EMX homeobox family.
Contains 1 homeobox DNA-binding domain. -
細胞内局在Nucleus.
- Information by UniProt
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参照データベース
- Entrez Gene: 523601 Cow
- Entrez Gene: 2018 Human
- Entrez Gene: 13797 Mouse
- Entrez Gene: 499380 Rat
- Omim: 600035 Human
- SwissProt: Q17R00 Cow
- SwissProt: Q04743 Human
- SwissProt: Q04744 Mouse
see all -
別名
- Empty spiracles homeobox 2 antibody
- Empty spiracles homolog 2 (Drosophila) antibody
- Empty spiracles homolog 2 antibody
see all
画像
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Western blot - Anti-EMX2 antibody (ab94713)All lanes : Anti-EMX2 antibody (ab94713) at 1 µg/ml
Lane 1 : Mouse Hippocampus Tissue Lysate
Lane 2 : Brain (Mouse) Tissue Lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 28 kDa
Additional bands at: 260 kDa (possible non-specific binding), 76 kDa (possible non-specific binding)
Exposure time: 16 minutes
参考文献
ab94713 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"