製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to EMX2
  • アプリケーション
    適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Recombinant fragment
    交差が予測される動物種: Mouse, Human
  • 免疫原

    Three synthetic peptides derived from human EMX2, conjugated to KLH.

  • ポジティブ・コントロール
    • An anti thio tested on an induced culture of E.coli.

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab86004 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
  • 追加情報
    Direct ELISA: 1/19000.
    WB: 1/1000. Predicted molecular weight: 28 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
    • 組織特異性
      Cerebral cortex.
    • 関連疾患
      Defects in EMX2 are the cause of schizencephaly (SCHZC) [MIM:269160]. Schizencephaly is an extremely rare human congenital disorder characterized by a full-thickness cleft within the cerebral hemispheres. These clefts are lined with gray matter and most commonly involve the parasylvian regions. Large portions of the cerebral hemispheres may be absent and replaced by cerebro-spinal fluid.
    • 配列類似性
      Belongs to the EMX homeobox family.
      Contains 1 homeobox DNA-binding domain.
    • 細胞内局在
      Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Empty spiracles homeobox 2 antibody
      • Empty spiracles homolog 2 (Drosophila) antibody
      • Empty spiracles homolog 2 antibody
      • Empty spiracles like protein 2 antibody
      • Empty spiracles-like protein 2 antibody
      • EMX 2 antibody
      • EMX2 antibody
      • EMX2_HUMAN antibody
      • Homeobox protein EMX 2 antibody
      • Homeobox protein EMX2 antibody
      see all

    画像

    • Lane 1 : Anti-EMX2 antibody (ab86004) at 1/1000 dilution (in 5% non fat milk PBST solution incubated for 60 minutes)
      Lane 2 : Anti-EMX2 antibody (ab86004) (in 5% non fat milk PBST solution incubated for 60 minutes)

      Lane 1 : uninduced culture of E. coli (plus anti thio at 1/5000 dilution)
      Lane 2 : induced culture of E. coli (plus anti thio at 1/5000 dilution)

      Secondary
      anti-Rabbit IgG HRP conjugate incubated for 60 minutes at 1/1000 dilution

      Predicted band size : 28 kDa
      Observed band size : 42 kDa (why is the actual band size different from the predicted?)

    プロトコール

    参考文献

    ab86004 has not yet been referenced specifically in any publications.

    レビューと Q&A

    There are currently no Customer reviews or Questions for ab86004.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    登録