製品の概要
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製品名Anti-EMR3 antibody
EMR3 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to EMR3
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由来種Rabbit
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アプリケーション適用あり: WB, ELISAmore details
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種交差性交差種: Human
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免疫原
Synthetic peptide derived from the C-terminal of human EMR3.
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ポジティブ･コントロール
- Extracts from Jurkat cells.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
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バッファーPreservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4 -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab75283 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | 1/500 - 1/1000. Predicted molecular weight: 73 kDa. | |
| ELISA | 1/10000. |
ターゲット情報
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関連性EMR3 is a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing of this gene results in two transcript variants encoding two distinct isoforms. EMR3 has been reported to be expressed in neutrophils, monocytes, and macrophages. ESTs have been isolated from liver/spleen and mixed libraries.
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細胞内局在Cell membrane; Multi-pass membrane protein. EMR3 subunit alpha: Secreted, extracellular space. Note: A soluble form is also detected.
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参照データベース
- Entrez Gene: 84658 Human
- Omim: 606101 Human
- SwissProt: Q9BY15 Human
- Unigene: 658712 Human
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別名
- Egf like module containing mucin like hormone receptor like 3 antibody
- Egf like module containing mucin like receptor 3 antibody
- EGF like module containing mucin like receptor EMR3 antibody
- EMR 3 antibody
画像
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Western blot - Anti-EMR3 antibody (ab75283)All lanes : Anti-EMR3 antibody (ab75283) at 1/500 dilution
Lane 1 : Extracts from Jurkat cells
Lane 2 : Extracts from Jurkat cells with immunising peptide at 10 µg
Lysates/proteins at 30 µg per lane.
Predicted band size: 73 kDa
Observed band size: 73 kDa
Additional bands at: 30 kDa, 40 kDa, 45 kDa. We are unsure as to the identity of these extra bands.
プロトコール
参考文献
ab75283 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"