Anti-EMR3 抗体 (ab75283)

製品の概要

• 製品名Anti-EMR3 antibody
  EMR3 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to EMR3
• アプリケーション適用あり: WB, ELISAmore details
• 種交差性
  交差種: Human
  
• 免疫原

  Synthetic peptide derived from the C-terminal of human EMR3.

• ポジティブ･コントロール
  • Extracts from Jurkat cells.

製品の特性

• 製品の状態Liquid
• 保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
• バッファーPreservative: 0.02% Sodium Azide
  Constituents: 50% Glycerol, PBS (without Mg²⁺ and Ca²⁺), 150mM Sodium chloride, pH 7.4
• Concentration information loading...
• 精製度Immunogen affinity purified
• ポリ/モノポリクローナル
• アイソタイプIgG
• 研究分野
  • Immunology
  • Innate Immunity
  • Macrophage / Inflamm.

  • Signal Transduction
  • Growth Factors/Hormones
  • EGF

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

アプリケーション

ターゲット情報

• 関連性EMR3 is a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing of this gene results in two transcript variants encoding two distinct isoforms. EMR3 has been reported to be expressed in neutrophils, monocytes, and macrophages. ESTs have been isolated from liver/spleen and mixed libraries.
• 細胞内局在Cell membrane; Multi-pass membrane protein. EMR3 subunit alpha: Secreted, extracellular space. Note: A soluble form is also detected.
• 参照データベース
  • Entrez Gene: 84658 Human
  • Omim: 606101 Human
  • SwissProt: Q9BY15 Human
  • Unigene: 658712 Human
• 別名
  • Egf like module containing mucin like hormone receptor like 3 antibody
  • Egf like module containing mucin like receptor 3 antibody
  • EGF like module containing mucin like receptor EMR3 antibody
  • EMR 3 antibody