製品の概要

  • 製品名Anti-EMR3 antibody
    EMR3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to EMR3
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to the C Terminal cytoplasmic domain of Human EMR3.

  • ポジティブ・コントロール
    • Human Macrophages.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab115460 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 関連性EMR3 is a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing of this gene results in two transcript variants encoding two distinct isoforms. EMR3 has been reported to be expressed in neutrophils, monocytes, and macrophages. ESTs have been isolated from liver/spleen and mixed libraries.
  • 細胞内局在Cell membrane; Multi-pass membrane protein. EMR3 subunit alpha: Secreted, extracellular space. Note: A soluble form is also detected.
  • 参照データベース
  • 別名
    • Egf like module containing mucin like hormone receptor like 3 antibody
    • Egf like module containing mucin like receptor 3 antibody
    • EGF like module containing mucin like receptor EMR3 antibody
    • EMR 3 antibody

Anti-EMR3 antibody 画像

  • ab115460 at 2.5 µg/ml staining EMR3 in Formalin-fixed, Paraffin-embedded Human Macrophages by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-EMR3 antibody (ab115460) 使用論文

ab115460 has not yet been referenced specifically in any publications.

Product Wall

I am sorry this product did not perform as stated on the datasheet and for the inconvenience this has caused. As requested, I have issued a free of charge replacement for one vial of ab58810.

To check the status of the order please contact o...

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Thanks for your reply.

I would be happy to send a vial of ab58810 as a replacement.

Woud this be alright?

Thanks for sending along the additional protocol details.

If this vial of ab115460 was received within 6 months or so of your initial complaint, I would be happy to offera replacement or credit if you like.

We do have 2 other EMR3 a...

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Thanks for your reply. I look forward to seeing your protocol.

We do have 2 other EMR3 antibodies, ab75283 and ab59146.

Thanks again for the additional information.

Hi Michael, my name is Jeremy Kasanov and I'm a member of the Scientific Support team at Abcam. Peter has forwarded me your email.

Perhaps you could provide a bit more details regarding the sample preparation and staining protocol. I will be ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"