製品の概要

  • 製品名Anti-EMR2 antibody
    EMR2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to EMR2
  • 特異性ab75190 detects endogenous levels of total EMR2 protein.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide derived from an internal region of human EMR2

  • ポジティブ・コントロール
    • HeLa cell extract

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab75190 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab75190 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 91 kDa.
ELISA 1/5000.

ターゲット情報

  • 機能Receptor probably involved in cell attachment.
  • 組織特異性Expression is restricted to myeloid cells. Highest expression was found in peripheral blood leukocytes, followed by spleen and lymph nodes, with intermediate to low levels in thymus, bone marrow, fetal liver, placenta, and lung, and no expression in heart, brain, skeletal muscle, kidney, or pancreas. Expression is also detected in monocyte/macrophage and Jurkat cell lines but not in other cell lines tested.
  • 配列類似性Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 5 EGF-like domains.
    Contains 1 GPS domain.
  • ドメインThe GPS domain is necessary, but not sufficient for receptor cleavage, which require the entire extracellular stalk.
    Binding to chondroitin sulfate is mediated by the fourth EGF domain.
  • 翻訳後修飾Autoproteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane beta subunit.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD 312 antibody
    • CD 312 antigen antibody
    • CD312 antibody
    • CD312 antigen antibody
    • Egf like module containing mucin like hormone receptor like 2 antibody
    • Egf like module containing mucin like hormone receptor like sequence 2 antibody
    • EGF like module EMR2 antibody
    • EGF-like module receptor 2 antibody
    • EGF-like module-containing mucin-like hormone receptor-like 2 antibody
    • EMR2 antibody
    • EMR2_HUMAN antibody
    see all

Anti-EMR2 antibody 画像

  • All lanes : Anti-EMR2 antibody (ab75190) at 1/500 dilution

    Lane 1 : HeLa cell extract
    Lane 2 : HeLa cell extract with immunising peptide at 10 µg

    Lysates/proteins at 10 µg per lane.


    Predicted band size : 91 kDa
    Observed band size : 91 kDa

Anti-EMR2 antibody (ab75190) 使用論文

ab75190 has not yet been referenced specifically in any publications.

Product Wall

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Thank you for sending me this further information. It has helped tremendously in understanding the issues that you have been facing.

I agree with your assessment that these bands are either non-specific or isoforms 4 and 5. As we cannot be s...

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I am sorry about the issues you have been having. Thank you for bringing this to our attention. As this product should not be recognizing the other forms of EMR2 it appears that you may be experiencing non specific background issues. I may be able to h...

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I have had to opportunity to speak with the lab further regarding this. The immunogen sequence for this product is:XXX which spans aaXXX-XXX (SwissProt: Q9UHX3Human). This sequence is within the excellular region and is not in isoforms 4 and 5. Are ...

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Thank you for contacting us.

I have had the opportunity to speak with the labs in regard to your questions about these product.

The immunogen sequence for each product is proprietary but the labs have run alignments and checked ...

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