製品の概要

  • 製品名Anti-ELOVL4 antibody
    ELOVL4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ELOVL4
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide derived from the internal of Human ELOVL4

  • ポジティブ・コントロール
    • Extracts from HeLa cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab110047 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 37 kDa.

ターゲット情報

  • 機能Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Elongates C24:0 and C26:0 acyl-CoAs. Seems to represent a photoreceptor-specific component of the fatty acid elongation system residing on the endoplasmic reticulum. May be implicated in docosahexaenoic acid (DHA) biosynthesis, which requires dietary consumption of the essential alpha-linolenic acid and a subsequent series of three elongation steps.
  • 組織特異性Expressed in the retina and at much lower level in the brain. Ubiquitous, highest expression in thymus, followed by testis, small intestine, ovary, and prostate. Little or no espression in heart, lung, liver, or leukocates.
  • 関連疾患Defects in ELOVL4 are the cause of Stargardt disease type 3 (STGD3) [MIM:600110]. STGD is one of the most frequent causes of macular degeneration in childhood. It is characterized by macular dystrophy with juvenile-onset, rapidly progressive course, alterations of the peripheral retina, and subretinal deposition of lipofuscin-like material. STGD3 inheritance is autosomal dominant.
  • 配列類似性Belongs to the ELO family.
  • ドメインThe di-lysine motif may confer endoplasmic reticulum localization.
  • 細胞内局在Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 3-keto acyl-CoA synthase ELOVL4 antibody
    • ADMD antibody
    • Cancer/testis antigen 118 antibody
    • CT118 antibody
    • Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 4 antibody
    • Elongation of very long chain fatty acids like 4 antibody
    • Elongation of very long chain fatty acids protein 4 antibody
    • ELOV L4 antibody
    • ELOV4_HUMAN antibody
    • ELOVL 4 antibody
    • ELOVL4 antibody
    • FLJ17667 antibody
    • FLJ92876 antibody
    • Stargardt disease 3 antibody
    • Stargardt disease 3 autosomal dominant antibody
    • STGD 2 antibody
    • STGD 3 antibody
    • STGD2 antibody
    • STGD3 antibody
    see all

Anti-ELOVL4 antibody 画像

  • All lanes : Anti-ELOVL4 antibody (ab110047) at 1/500 dilution

    Lane 1 : extracts from HeLa cells
    Lane 2 : extracts from HeLa cells with blocking peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 37 kDa

Anti-ELOVL4 antibody (ab110047) 使用論文

ab110047 has not yet been referenced specifically in any publications.

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