製品の概要

  • 製品名Ellagic acid
  • 製品の詳細
    Selective, casein kinase 2 (CK2) inhibitor
  • 生理活性の詳細Selective, ATP-competitive casein kinase 2 (CK2) inhibitor (Ki = 20 nM). Exhibits a multitude of biological activities including antioxidant, antiproliferative and pro-apoptotic activity.
  • 精製度> 99%

製品の特性

  • 体系名2,3,7,8-Tetrahydroxy[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione
  • 分子量302.20
  • 構造式Chemical Structure
  • 分子式C14H6O8
  • CAS 番号476-66-4
  • 保存方法Store at -20°C. Store at -20°C long term. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under Desiccating conditions.
  • 溶解性Soluble in DMSO to 1 mM and in ethanol to 1 mM
  • 使用に関する注意

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • 由来

    Tree bark

  • 研究分野

    Ellagic acid (ab120622) 使用論文

    This product has been referenced in:
    • Cozza G  et al. Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J Med Chem 49:2363-6 (2006). Read more (PubMed: 16610779) »
    • Seeram NP  et al. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. J Nutr Biochem 16:360-7 (2005). Read more (PubMed: 15936648) »
    • Han DH  et al. Antioxidant and apoptosis-inducing activities of ellagic acid. Anticancer Res 26:3601-6 (0). Read more (PubMed: 17094489) »

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"