製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to ELF5
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig, Spider monkey
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 101-150 (AGICGEYLYF ILQNIRSQGY SFFNDAEETK TGIKDYADSS CLKTSGIKSQ) of Mouse Elf5 (NP_034255).

  • ポジティブ・コントロール
    • Mouse kidney lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab104410 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 30 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Transcriptionally activator that may play a role in regulating the later stages of keratinocytes terminal differentiation.
    Isoform 2 binds to DNA sequences containing the consensus nucleotide core sequence GGA[AT]. Transcriptionally activates SPRR2A and the parotid gland-specific PSP promoters.
  • 組織特異性
    Expressed exclusively in tissues with a high content of epithelial cells. Highly expressed in salivary gland, mammary gland, kidney and prostate. Weakly expressed in placenta and lung. Isoform 1 and isoform 2 are differentially expressed in different tissues. In the kidney, only isoform 1 was expressed, while prostate expressed both isoforms, with levels of isoform 2 being higher. Expression is up-regulated during keratinocyte differentiation. Several epithelial carcinoma cell lines showed lack of expression.
  • 配列類似性
    Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
    Contains 1 PNT (pointed) domain.
  • ドメイン
    The PNT domain acts as a transcriptional activator.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • E74 like factor 5 (ets domain transcription factor) antibody
    • E74 like factor 5 antibody
    • E74-like factor 5 antibody
    • ELF 5 antibody
    • ELF5 antibody
    • ELF5_HUMAN antibody
    • Epithelium restricted ESE 1 related Ets factor antibody
    • Epithelium restricted ESE1 related Ets factor antibody
    • Epithelium specific Ets transcription factor 2 antibody
    • Epithelium-restricted ESE-1-related Ets factor antibody
    • Epithelium-specific Ets transcription factor 2 antibody
    • ESE 2 antibody
    • ESE-2 antibody
    • ESE2 antibody
    • Ets domain TF antibody
    • Ets domain transcription factor antibody
    • ETS related transcription factor Elf 5 antibody
    • ETS related transcription factor Elf5 antibody
    • ETS-related transcription factor Elf-5 antibody
    see all

画像

  • Anti-ELF5 antibody (ab104410) at 1 µg/ml + Mouse kidney lysate at 10 µg

    Predicted band size : 30 kDa

プロトコール

参考文献

ab104410 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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