Anti-Elafin/ESI 抗体 [TRAB2F] (ab81681)
Key features and details
- Mouse monoclonal [TRAB2F] to Elafin/ESI
- Suitable for: ELISA, IHC-P, WB
- Reacts with: Human
- Isotype: IgG2b
製品の概要
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製品名
Anti-Elafin/ESI antibody [TRAB2F]
Elafin/ESI 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [TRAB2F] to Elafin/ESI -
由来種
Mouse -
アプリケーション
適用あり: ELISA, IHC-P, WBmore details
適用なし: IHC-Fr -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Elafin/ESI (C terminal) conjugated to keyhole limpet haemocyanin.
Sequence:AQEPVKGPVSTKPGSC
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.02% Sodium azide
Constituents: 1% BSA, PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
TRAB2F -
アイソタイプ
IgG2b -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab81681の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
Use at an assay dependent concentration.
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IHC-P |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 12 kDa.
Use under reducing conditions. |
特記事項 |
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ELISA
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. Predicted molecular weight: 12 kDa. Use under reducing conditions. |
ターゲット情報
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機能
Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis. -
配列類似性
Contains 1 WAP domain. -
ドメイン
Consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain serves as an anchor to localize elafin covalently to specific sites on extracellular matrix proteins. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 5266 Human
- Omim: 182257 Human
- SwissProt: P19957 Human
- Unigene: 112341 Human
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別名
- Cementoin antibody
- ELAF_HUMAN antibody
- Elafin antibody
see all
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab81681 は 3 報の論文で使用されています。
- Zakizadeh F et al. Upregulation of elafin expression in the fallopian tube of ectopic tubal pregnancies compared to the normal tubes. J Reprod Immunol 141:103136 (2020). PubMed: 32485443
- Curciarello R et al. Human Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies. J Inflamm Res 13:233-243 (2020). PubMed: 32547155
- Desmet E et al. Towards the development of a RNAi-based topical treatment for psoriasis: Proof-of-concept in a 3D psoriasis skin model. Exp Dermatol 27:463-469 (2018). PubMed: 28833576