製品の概要

  • 製品名Anti-EIF5AL1 antibody
  • 製品の詳細
    Rabbit polyclonal to EIF5AL1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 101-130 of Human EIF5AL1 (NP_001093162.1)

  • ポジティブ・コントロール
    • Ramos cell line lysates

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab110502 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 17 kDa.

ターゲット情報

  • 機能mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation.
  • 配列類似性Belongs to the eIF-5A family.
  • 翻訳後修飾eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine).
  • 細胞内局在Cytoplasm. Nucleus. Endoplasmic reticulum membrane. Nucleus > nuclear pore complex. Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions.
  • Information by UniProt
  • 参照データベース
  • 別名
    • bA342M3.3 antibody
    • eIF-5A-1-like antibody
    • eIF-5A1-like antibody
    • EIF5AL1 antibody
    • EIF5AP1 antibody
    • Eukaryotic initiation factor 5A isoform 1-like antibody
    • Eukaryotic translation initiation factor 5A-1-like antibody
    • IF5AL_HUMAN antibody
    • RP11-342M3.3 antibody
    see all

Anti-EIF5AL1 antibody 画像

  • Anti-EIF5AL1 antibody (ab110502) at 1/100 dilution + Ramos cell line lysates at 35 µg

    Predicted band size : 17 kDa

Anti-EIF5AL1 antibody (ab110502) 使用論文

ab110502 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"