The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Detects a band of approximately 30 kDa (predicted molecular weight: 28 kDa).
1/50 - 1/100.
機能Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
配列類似性Belongs to the eukaryotic initiation factor 4E family.
翻訳後修飾Ubiquitinated by ARIH1, leading to its degradation by the proteasome.