Anti-eIF4EBP1 (phospho T45) 抗体 (ab47367)

製品の概要

  • 製品名Anti-eIF4EBP1 (phospho T45) antibody
    eIF4EBP1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to eIF4EBP1 (phospho T45)
  • 特異性ab47367 detects endogenous levels of 4EBP1 only when phosphorylated at threonine 45. This antibody may cross-react with 4EBP2 and 4EBP3 when phosphorylated at equivalent sites.
  • アプリケーション適用あり: WB, IHC-P, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    The antiserum was produced against synthesized phosphopeptide derived from human 4EBP1 around the phosphorylation site of threonine 45 (S-T-TP-P-G).

  • ポジティブ・コントロール
    • MDA435 cells, breast carcinoma tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab47367 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 13 kDa.
IHC-P Use at an assay dependent concentration.
ELISA 1/20000.

ターゲット情報

  • 機能Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
  • 配列類似性Belongs to the eIF4E-binding protein family.
  • 翻訳後修飾Phosphorylated on serine and threonine residues in response to insulin, EGF and PDGF. Phosphorylation at Thr-37, Thr-46, Ser-65 and Thr-70 is regulated by mTORC1. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 4E-BP1 antibody
    • 4EBP1 antibody
    • 4EBP1_HUMAN antibody
    • BP 1 antibody
    • eIF4E binding protein 1 antibody
    • eIF4E-binding protein 1 antibody
    • Eif4ebp1 antibody
    • Eukaryotic translation initiation factor 4E-binding protein 1 antibody
    • PHAS-I antibody
    • PHASI antibody
    • Phosphorylated heat- and acid-stable protein regulated by insulin 1 antibody
    see all

Anti-eIF4EBP1 (phospho T45) antibody 画像

  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ab47367. Left hand image without immunising peptide; right hand image with immunising peptide.


  • Predicted band size : 13 kDa

Anti-eIF4EBP1 (phospho T45) antibody (ab47367) 使用論文

ab47367 has not yet been referenced specifically in any publications.

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