製品の概要

  • 製品名Anti-eIF4EBP1 antibody
    eIF4EBP1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to eIF4EBP1
  • アプリケーション適用あり: ICC/IF, WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    14 amino acid synthetic peptide from near the C terminus of eIF4EBP1 (Human).

  • ポジティブ・コントロール
    • 3T3 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab25872 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 2 µg/ml.
WB Use a concentration of 2.5 - 5 µg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 13 kDa).

ターゲット情報

  • 機能Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
  • 配列類似性Belongs to the eIF4E-binding protein family.
  • 翻訳後修飾Phosphorylated on serine and threonine residues in response to insulin, EGF and PDGF. Phosphorylation at Thr-37, Thr-46, Ser-65 and Thr-70 is regulated by mTORC1. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 4E-BP1 antibody
    • 4EBP1 antibody
    • 4EBP1_HUMAN antibody
    • BP 1 antibody
    • eIF4E binding protein 1 antibody
    • eIF4E-binding protein 1 antibody
    • Eif4ebp1 antibody
    • Eukaryotic translation initiation factor 4E-binding protein 1 antibody
    • PHAS-I antibody
    • PHASI antibody
    • Phosphorylated heat- and acid-stable protein regulated by insulin 1 antibody
    see all

Anti-eIF4EBP1 antibody 画像

  • Lane 1 : Anti-eIF4EBP1 antibody (ab25872) at 2.5 µg/ml
    Lane 2 : Anti-eIF4EBP1 antibody (ab25872) at 5 µg/ml
    Lane 3 : Anti-eIF4EBP1 antibody (ab25872) at 10 µg/ml

    Lane 1 : Human brain cell lysate
    Lane 2 : Human brain cell lysate
    Lane 3 : Human brain cell lysate


    Predicted band size : 13 kDa
  • ab25872 at 2µg/ml staining elf4EBP1 in 3T3 cells by ICC/IF

Anti-eIF4EBP1 antibody (ab25872) 使用論文

ab25872 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"