製品の概要

  • 製品名Anti-eIF4E (phospho S209) antibody
    eIF4E 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to eIF4E (phospho S209)
  • 特異性This antibody is specific for elF4E, only when phosphorylated at serine 209.
  • アプリケーション適用あり: ELISA, WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat
  • 免疫原

    A synthesized phosphopeptide derived from human elF4E around the phosphorylation site of serine 209 (S-G-SP-T-T)

  • ポジティブ・コントロール
    • WB: Extracts from NIH/3T3 cells IHC: Human breast carcinoma tissue

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab47605 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/20000.
WB 1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 25 kDa).
IHC-P Use at an assay dependent concentration.

ターゲット情報

  • 機能Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1 (By similarity). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
  • 配列類似性Belongs to the eukaryotic initiation factor 4E family.
  • 翻訳後修飾Phosphorylation increases the ability of the protein to bind to mRNA caps and to form the eIF4F complex.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AUTS19 antibody
    • CBP antibody
    • eIF 4E antibody
    • eIF 4F 25 kDa subunit antibody
    • EIF 4F antibody
    • eIF-4E antibody
    • eIF-4F 25 kDa subunit antibody
    • eIF4E antibody
    • EIF4E1 antibody
    • EIF4EL1 antibody
    • EIF4F antibody
    • Eukaryotic translation initiation factor 4 E antibody
    • Eukaryotic translation initiation factor 4E antibody
    • Eukaryotic translation initiation factor 4E like 1 antibody
    • IF4E_HUMAN antibody
    • Messanger RNA Cap Binding Protein eIF 4E antibody
    • MGC111573 antibody
    • mRNA cap binding protein antibody
    • mRNA cap-binding protein antibody
    see all

Anti-eIF4E (phospho S209) antibody 画像

  • All lanes : Anti-eIF4E (phospho S209) antibody (ab47605) at 1/500 dilution

    Lane 1 : Extracts from NIH/3T3 cells, treated with FBS. No peptide.
    Lane 2 : Extracts from NIH/3T3 cells, not treated with FBS. No peptide.

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 25 kDa
    Observed band size : 25 kDa
  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ab47605 at a 1/50 dilution.

Anti-eIF4E (phospho S209) antibody (ab47605) 使用論文

ab47605 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab47605.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"