製品の概要

  • 製品名
  • 製品の詳細
    Chicken polyclonal to EIF3S2
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide, corresponding to N terminal amino acids 1-230 of Human EIF3S2.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab37526 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).
ELISA Use a concentration of 1 µg/ml.

ターゲット情報

  • 機能
    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
  • 配列類似性
    Belongs to the eIF-3 subunit I family.
    Contains 5 WD repeats.
  • 翻訳後修飾
    Phosphorylated by TGF-beta type II receptor.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • eIF-3-beta antibody
    • eIF3 beta antibody
    • eIF3 p36 antibody
    • eIF3-beta antibody
    • eIF3-p36 antibody
    • eIF3i antibody
    • EIF3I_HUMAN antibody
    • EIF3S2 antibody
    • EIF3S2, formerly antibody
    • Eukaryotic translation initiation factor 3 subunit 2 antibody
    • Eukaryotic translation initiation factor 3 subunit 2 beta antibody
    • Eukaryotic translation initiation factor 3 subunit I antibody
    • eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD antibody
    • eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa antibody
    • eukaryotic translation initiation factor 3, subunit 2, formerly antibody
    • eukaryotic translation initiation factor 3, subunit I antibody
    • Predicted protein of HQ2242 antibody
    • PRO2242 antibody
    • TGF beta receptor interacting protein 1 antibody
    • TGF-beta receptor-interacting protein 1 antibody
    • TGFbeta receptor interacting protein 1 antibody
    • TGFbeta receptor-interacting protein 1 antibody
    • TRIP 1 antibody
    • TRIP-1 antibody
    • TRIP1 antibody
    see all

画像

  • Direct ELISA test. Serial dilutions of Human EIF3S2 protein were used as test antigen. ab37526 was used as test antibody at 1µg/ml. Goat anti-IgY-HRP was used as secondary antibody.
  • Anti-EIF3S2 antibody (ab37526) at 1/2000 dilution + E. coli derived fusion protein at 2.5 µg

    Secondary
    Goat anti-IgY-HRP at 1/1000 dilution

    Predicted band size : 37 kDa
    Observed band size : 37 kDa

プロトコール

参考文献

This product has been referenced in:
  • Angelucci S  et al. Proteome analysis of human Wharton's jelly cells during in vitro expansion. Proteome Sci 8:18 (2010). WB ; Human . Read more (PubMed: 20346146) »

See 1 Publication for this product

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