製品の概要

  • 製品名Anti-eIF3B antibody
    eIF3B 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to eIF3B
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 100-150 of Human eIF3B (NP_003742.2)

  • ポジティブ・コントロール
    • Human: breast carcinoma; colon carcinoma; non-small cell lung cancer; ovarian carcinoma; prostate carcinoma; stomach adenocarcinoma; testicular seminoma (FFPE sections). Mouse: colon carcinoma CT26; renal cell carcinoma; teratoma (FFPE sections).

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium azide
    Constituents: 0.1% BSA, 99% Tris buffered saline
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab113218 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

ターゲット情報

  • 機能Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
  • 配列類似性Belongs to the eIF-3 subunit B family.
    Contains 1 RRM (RNA recognition motif) domain.
    Contains 5 WD repeats.
  • ドメインThe RRM domain mediates interaction with EIF3J.
  • 翻訳後修飾Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • eIF-3-eta antibody
    • eIF3 eta antibody
    • eIF3 p110 antibody
    • eIF3 p116 antibody
    • EIF3-ETA antibody
    • EIF3-P110 antibody
    • EIF3-P116 antibody
    • eIF3b antibody
    • EIF3B_HUMAN antibody
    • EIF3S9 antibody
    • EIF3S9, formerly antibody
    • Eukaryotic translation initiation factor 3, subunit B antibody
    • Eukaryotic translation initiation factor 3 subunit 9 antibody
    • eukaryotic translation initiation factor 3 subunit 9 eta antibody
    • Eukaryotic translation initiation factor 3 subunit B antibody
    • eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD) antibody
    • eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa antibody
    • eukaryotic translation initiation factor 3, subunit 9, formerly antibody
    • hPrt1 antibody
    • Protein synthesis defective at 36 degrees celsius 1, S. cerevisiae, homolog of antibody
    • PRT1 antibody
    • Prt1 homolog antibody
    see all

Anti-eIF3B antibody 画像

  • ab113218 at a 1/100 dilution staining eIF3B in Human ovarian carcinoma by immunohistochemistry (FFPE section). Secondary antibody used was Red-fluorescent Goat anti-Rabbit IgG-heavy and light chain cross-adsorbed DyLight® 594 Conjugated at a dilution of 1/100.
  • ab113218 at a 1/500 dilution staining eIF3B in Human ovarian carcinoma by immunohistochemistry (FFPE section).
  • ab113218 at a 1/100 dilution staining eIF3B in Mouse teratoma by immunohistochemistry (FFPE section).

Anti-eIF3B antibody (ab113218) 使用論文

ab113218 has not yet been referenced specifically in any publications.

Product Wall

Vielen Dank für Ihre Antwort. Hier ist eine Liste mit den Homologien der Immunogene zu Kaninchen der folgenden Antikörper: eIF3B ABCF1=ABC50 ab40799 100% ab89109 92% ab113218 45% ...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"