製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to EID2
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Guinea pig, Cow, Dog, Human
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 155-204 (

    QFLRHYLENYPIAPGRIQELEERRRRFVEACRAREAAFDIEYLRNPQRVD

    ) of Mouse EID2 (NM_198425).

  • ポジティブ・コントロール
    • Mouse kidney lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab125373 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 26 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.
  • 組織特異性
    Most abundantly expressed in placenta. Highly expressed in liver, brain, heart, skeletal muscle, and kidney.
  • ドメイン
    The N-terminal portion of EID2 is required for nuclear localization.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CREBBP/EP300 inhibitor 2 antibody
    • CREBBP/EP300 inhibitory protein 2 antibody
    • CRI2 antibody
    • E1A like inhibitor of differentiation 2 antibody
    • EID-1-like inhibitor of differentiation 2 antibody
    • EID-2 antibody
    • EID2 antibody
    • EID2_HUMAN antibody
    • EP300-interacting inhibitor of differentiation 2 antibody
    see all

画像

  • Anti-EID2 antibody (ab125373) at 1 µg/ml + Mouse kidney lysate at 10 µg

    Predicted band size : 26 kDa

プロトコール

参考文献

ab125373 has not yet been referenced specifically in any publications.

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