製品の概要

  • 製品名Anti-EID1 antibody
    EID1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to EID1
  • アプリケーション適用あり: IP, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide:

    GSGSRELSLRPSRSGA

    conjugated to KLH, corresponding to C terminal amino acids 34-49 of Human EID1.

  • ポジティブ・コントロール
    • EID1 transfected Cos1 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab14454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use a concentration of 10 µg/ml.
WB Use a concentration of 2 - 4 µg/ml. Predicted molecular weight: 22 kDa.

ターゲット情報

  • 機能Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms.
  • 組織特異性Widely expressed. Most abundantly expressed in heart, skeletal muscle, pancreas, brain and testis. Expressed at much lower levels in placenta and peripheral blood leukocyte. Barely detectable in lung. Also weakly expressed in lung carcinoma A549 and various leukemia cell lines.
  • 発生段階Expression decreased with development in ventricular tissue while remaining highly expressed in adult atrial tissue. In primary cultures of human skeletal myocytes, expression decreased during myogenic differentiation (at protein level).
  • 翻訳後修飾Ubiquitinated in U-2OS osteosarcoma cells and is rapidly degraded by proteasome as cells exit the cell cycle exit.
  • 細胞内局在Nucleus. Cytoplasm. May shuttle between nucleus and cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 21 kDa pRb associated protein antibody
    • 21 kDa pRb-associated protein antibody
    • C15orf3 antibody
    • CBP antibody
    • Chromosome 15 open reading frame 3 antibody
    • CREBBP/EP300 inhibitor 1 antibody
    • CREBBP/EP300 inhibitory protein 1 antibody
    • CRI 1 antibody
    • CRI1 antibody
    • E1A like inhibitor of differentiation antibody
    • E1A-like inhibitor of differentiation 1 antibody
    • EID 1 antibody
    • EID-1 antibody
    • EID1 antibody
    • EID1_HUMAN antibody
    • EP300 interacting inhibitor of differentiation 1 antibody
    • EP300-interacting inhibitor of differentiation 1 antibody
    • IRO45620 antibody
    • MGC138883 antibody
    • MGC138884 antibody
    • NB4 apoptosis related protein antibody
    • PNAS 22 antibody
    • PNAS22 antibody
    • PTD014 antibody
    • Rb and p300 binding protein EID 1 antibody
    • Rb and p300 binding protein EID1 antibody
    • RBP21 antibody
    • Retinoblastoma protein associated protein antibody
    see all

Anti-EID1 antibody (ab14454) 使用論文

ab14454 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry and for taking your time to fill in the on-line Questionnaire and for providing details of your Western blot protocol. I am very sorry to hear that you are having problem with this antibody. I have looked through your proc...

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Thank you for your enquiry regarding ab14454. We have not yet tested the cross-reactivity for this antibody with mouse tissue but expect the antibody to work as there is 90% similarity between mouse and human (which we have tested). Should you de...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"